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local hormones are produced where
local hormones are synthesized in various tissue types
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local hormones site of action
local hormones are released and act locally
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local hormones action
local hormones exert profound changes in the body
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systemic hormones are produced where
systemic hormones are produced by one specific tissue (gland)
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systemic hormones site of action
systemic hormones act through out the body
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systemic hormones action
systemic hormones have a regulatory effect
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histamine location
found in all tissues of the body
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histamine causes
- bronchial constriction
- stomach acid secretion
- blood vessel dilation
- local edema (swelling)
- pain
- itching
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prostaglandins causes
- uterine and bronchial contractions and relaxation
- decreased gastric secretions
- pain
- inflammation
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Antihistamines (Histamine Antagonists) uses
- Treatment of allergies, rashes, and hay fever
- Motion sickness, nausea, and dizziness
- H2 antagonist is used to treat ulcers and reflux disease
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Antihistamines (Histamine Antagonists) side effects
- Drowsiness
- CNC depression
- Anticholinergic effects
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why are sedating antihistamines considered a CNS drug?
They cross the blood brain barrier making them a CNS drug.
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do Non-Sedating Antihistamines type 1 cross the blood brain barrier
no
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Antihistamine - Type II, competitive blockers of histamine at the H2 receptors, those in the
stomach
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