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what does genitourinary surgery include?
procedures of the urethra, bladder, ureters, kidneys, and male reproductive system
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three common approaches used in GU surgery
- transurethral surgery
- open surgery
- minimally invasive surgery
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surgery performed through a flexible or rigid fiberoptic endoscope inserted through the external urethra, providing direct visualization and access to the lower urinary tract
transurethral surgery
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surgery performed through an open incision in the abdomen or flank
open surgery
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closed surgery performed using percutaneous endoscopic techniques (laparotomy)
minimally invasive surgery
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where does retroperitoneal cavity lie?
posterior to the peritoneal cavity
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serous membrane covering the retroperitoneal cavity on the anterior side
retroperitoneum
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primary organs for filtration of blood
kidneys
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where are the kidneys located?
in the retroperitoneal cavity at the level of the 12th thoracic vertebra
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which kidney sits lower than the other?
right
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how are the kidneys supported?
dense fascia and fatty tissue
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2 main tissue layers that make up the kidney
- cortex (outer layer)
- medulla (inner layer)
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covered with strong fibrous tissue and contains portions of the microscopic tubules that filter the blood
cortex
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composed of 8 to 12 large collecting areas (renal pyramids)
medulla
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notched area on the medial side of each kidney
hilum
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filtering units in the kidneys
nephrons
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how many nephrons are present in each kidney?
about 1 million
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capillary structure within the kidney that allows nephron to communicate with the vascular system to filter blood
glomerulus
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where is the capillary network of each nephron contained?
Bowman capsule
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how much fluid can the glomerulus filter per minute and what is this called?
- 125 mL
- glomerular filtration rate
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specific regions of the tubule system
- proximal tubule
- loop of Henle
- distal convoluted tubule
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what are formed by the precipitation of specific salts?
renal calculi
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decreased or no urinary output
anuria
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diseases in which kidney stones are seen
- hyperparathyroidism
- increased absorption of calcium in the intestine
- chronic urinary tract infection
- high protein intake
- use of some drugs
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how are calculi reduced?
with extra-corporeal shock wave lithotripsy (ESWL)
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paired organs that lie on the medial side of the upper kidney
adrenal glands
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what do the adrenal glands secrete?
corticosteroids and hormones necessary for metabolism
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how is blood supplied to each adrenal gland?
by aorta and branches of renal and inferior phrenic arteries
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how long is each ureter?
about 12 inches long and about 5 mm in diameter
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segmental contraction and relaxation of the ureter's muscular layer
peristalsis
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4 tissue layers of the bladder
- outer serosa
- muscular layer
- submucosa
- inner mucosa
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distal portion of the bladder
trigone
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what are the sphincter muscles of the bladder neck controlled by?
autonomic nervous system
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mucous-secreting glands located on each side of the urethra just inside the meatus
Skene's glands
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parts of the male urethra
- prostatic urethra - begins at bladder neck
- membranous urethra - midportion
- cavernous urethra - distal end
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layered tissue sac that encases the testicles
scrotum
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folds in the skin of the sacrum
rugae
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male reproductive cells
spermatozoa
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fibrous membrane enclosing testicles
tunica vaginalis
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smallest units of male ductal system
seminiferous tubules
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primary male sex hormone
testosterone
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convoluted duct that secretes seminal fluid
epididymis
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liquid substance that gives sperm mobility through male reproductive tract
seminal fluid
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joins epididymis with ejaculatory duct
vas deferens
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paired structures that secrete approximately 60% of the semen
seminal vesicles
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surrounds urethra and secretes alkaline fluid that contributes to seminal fluid
prostate gland
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glands that secrete mucus, which contributes to the total volume of the semen
bulbourethral glands or Cowper's glands
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what procedure is performed in patients with chronic end-stage renal disease?
kidney dialysis
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what is kidney dialysis?
procedure that performs normal kidney function
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2 types of kidney dialysis
- hemodialysis
- peritoneal dialysis
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dialysis in which blood is shunted into a heparinized machine
hemodialysis
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how long does hemodialysis normally last and how many times is it performed?
it lasts about 3 hours and performed 3 or 4 times a week
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major vein and artery are anastomosed by an implanted artificial graft for access to the vascular system during hemodialysis
arteriovenous fistula (AV shunt)
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dialysis in which a Silastic tube is implanted in the suprapubic peritoneal space and dialysis solution is instilled into the catheter
peritoneal hemodialysis
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stones formed by crystalline mineral and salts precipitated from filtrate produced in the kidney
calculi
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greatest risk factor for cancer of the kidney?
smoking
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primary cancer of the kidney arises from?
cortex and renal pelvis
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causes of end-stage renal disease
diabetes, hypertension, sysetmic lupus, nephrotic syndrome and infection
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most common tumors in children, arising in kidney
Wilms' tumor (nephroblastoma)
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overproduction of glucocorticoid
Cushing's syndrome
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most common form of urinary tract cancer
bladder cancer
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traumatic injury to the bladder occurs most often when?
motor vehicle accidents and related to pelvic fracture
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loss of sphincter control at the bladder neck
urinary incontinence
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UTI is commonly caused by?
E. coli contamination of distal urethra or by STD
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age-related enlargement of the prostate gland
benign prostatic hyperplasia (BPH)
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congenital anomaly in which one or both testicles fail to descend into scrotum in fetal life
cryptorchidism
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urethra open on top side of the penis or may be exposed along the full length
epispadius
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urethra fails to develop fully, resulting in urethral shortening and displacement of urethral meatus
hypospadius
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cancer that originates in the squamous cells of the glans or foreskin
penile cancer
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cancer that arises from the germ cell of the testicle
testicular cancer
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rotation of the testicle related to congenital anomaly or as a result of vigorous activity in young males - medical emergency
testicular torsion
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enlarged, dilated veins in the scrotum
varicocele
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primary function of the urinary system
filter metabolic waste from the blood
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how much urine do the kidneys produce per day?
about 3.2 pints (1.5 L) per day
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ratio of the density of urine compared to water
specific gravity
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primary protein component of the blood
albumin
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measures rate of creatinine clearance from the blood
glomerular filtration rate
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how is GFR measured?
as the amount of creatinine filtered per minute
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test that assesses the elimination of urea from the liver
blood urea nitrogen (BUN)
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preferred method for imaging tumors of the kidney
CT scan
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what is a noncontrast helical CT used to diagnose?
calculi
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what is IV urography used for?
- contrast medium is injected IV to obtain serial radiographs of the renal pelvis and calyces
- rate of emptying and size of ureters are also measured
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radiograph of kidney, ureters and bladder
KUB
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what is KUB used for?
to outline structures of the urinary system including stones larger than 2 mm
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test that provides images of the bladder while it is emptying
micturating cystourethrogram
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radiographic test commonly used in the diagnosis of tumors
MRI
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radiographic test used to detect metastasis arising from primary tumor of prostate
nuclear imaging
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how is retrograde ureteropyelogram performed?
- injections made using a catheter inserted into the ureter
- contrast medium instilled into the catheter and viewed with fluoroscopy
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radiographic test used for patients ineligible for CT or other forms of radiographic exposure
ultrasonography
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ureters require what type of instruments?
atraumatic clamps such as Babcocks
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what types of instruments are used to occlude vessels and for blunt dissection?
right-angle and Schnitz (tonsil) clamps
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what is the direct forward cystoscope used for?
has a 0-degree angle and is useful for viewing the urethra
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what is the right-angle cystoscope for?
has 30-degree angle and used for viewing the entire bladder and for insertion of ureteral catheters
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sizes of Brown-Buerger cystoscope
ranges from 14 to 26 French
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most common Brown-Buerger cystoscope size for adults
21 French
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hollow tube that serves as a passageway for the instruments used during cystoscopy and resection
sheath
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transurethral, electrosurgical instrument used to remove small fragments of tissue, cutting and coagulating target tissue inside the bladder
resectoscope
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most common type of resectoscope
Iglesias resectoscope
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urinary catheter sizes
ranging from 7 to 26 French
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purposes for urinary catheterization
- short-term urinary drainage
- continuous urinary drainage
- hemostasis and evacuation of blood clots or blood
- continuity of urethra or ureters
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used to apply pressure against a tissue or opening
tamponade
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surgery of the distal GU system performed with operative cystourethroscope
cystoscopy
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when is basic cystoscopy performed?
at the start of any transurethral procedure for visual assessment
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small incision made in the internal urethra to release scar tissue or other stricture
urethrotomy
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small incision is made in urethral meatus to relieve stricture
meatotomy
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most common complications of cystoscopic procedures
bleeding and edema
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most common cause of urinary obstruction
renal stones (calculi)
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specialized instrument that grasps and crushes renal stone
lithotrite
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procedure in which the prostate is removed with a resectoscope inserted through urethra
transurethral resection of prostate (TURP)
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nonmalignant enlargement of the prostate gland
benign prostatic hyperplasia (BPH)
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2 ways in which the prostate can enlarge
- cells multiply around urethra, causing obstruction
- cells grow into urethra and bladder outlet area
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backward flow of urine
reflux of urine
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in what position is the patient placed for TURP procedure?
lithotomy position
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during TURP, what type of irrigation fluid is used?
nonelectrolyte solution
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after resection, how long does Foley catheter remain?
12-24 hours
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possible postop complications of TURP
- incontinence
- impotence
- infertility
- passage of semen into the bladder
- urethral stricture
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congenital downward curvature of the penis
chordee
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principle of hypospadius repair
reconstruction of urethra using a graft from foreskin or buccal skin
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2 types of penile implants available
- semirigid implant
- inflatable reservoir implant
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where is cylinder from the penile implant placed during insertion?
in the corpora cavernosa of the penis
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ligation of the veins of the testes to reduce venous backflow of blood into internal spermatic veins, done to improve spermatogenesis
varicocelectomy
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vascular abnormality in which the pampiniform venous plexus of the scrotum is dilated
varicocele
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benign, fluid-filled sac that develops in the anterior testis
hydrocele
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surgical removal of one or both testicles
orchiectomy
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twisting of the testis, resulting in ischemia and necrosis
torsion
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removing section of vas deferens and sealing the free ends, preventing the movement of sperm through the ejaculatory ducts
vasectomy
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surgical anastomosis of vas deferens to restore continuity after vasectomy
vasovasostomy
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insertion of suprapubic catheter into the bladder for drainage through a percutaneous or open approach
suprapubic cystostotomy
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total or partial removal of the bladder, most often to treat bladder cancer
cystectomy
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second most common cancer of the GU system
bladder cancer
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for what is cystectomy indicated?
small, invasive tumors that penetrate the bladder wall
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procedure in which a functional bladder is constructed with a loop of bowel that is brought out of the abdominal wall
ileal conduit
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suspension of the bladder neck and urethra to the cartilage of the pubic symphysis to treat urinary stress incontinence in the female
vesicourethral suspension (Marshall-Marchetti-Krantz procedure)
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what is overflow incontinence caused by?
overactive detrusor muscle with normal urethra
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procedure in which bladder neck is held in suspension with biosynthetic strip or fascia graft which is attached to abdominal wall
pubovaginal sling
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removal of a prostatic adenoma through a perineal approach
perineal prostatectomy
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initial tests to diagnose prostate cancer
PSA and digital rectal examination
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why is suprapubic prostatectomy performed?
treatment of BPH and prostate cancer
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removal of tissue or organ without previous fragmentation or dissection
enucleation
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distention of renal pelvis and proximal ureter caused by obstruction in ureter and reflux of kidney filtrate
hydronephrosis
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reconstruction of the ureter at the level of the renal pelvis
pyeloplasty
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procedure of the ureter
uretero
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reconstruction of the ureter
ureteroplasty
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anastomosis of the ureter with another hollow structure to provide continuity
ureterostomy
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crossing of one ureter to another to create an anastomosis between the two ureters
transureteroureterostomy
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reimplantation of the ureter in the bladder
vesicoureterostomy
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large stones in the kidney or upper ureter are removed percutaneously through nephroscope
percutaneous nephrolithotomy
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what type of irrigation solution is used to flush the operative site during nephroscopy?
warm isotonic irrigation fluid (0.9% saline)
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surgical removal of one kidney
simple nephrectomy
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