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blood bank blood storage
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Red blood cells/whole blood storage requirements?
21 days - CPD
35 days - CPDA-1
42 days - Additive soln
All at 1 - 6 deg C
Frozen RBCs storage requirements?
10 years at -65 deg C, 24 hours post thaw
Washed RBCs storage requirements?
24 hours at 1-6 deg C
Platelets storage requirements?
5 days at 20-24 deg C with gentle aggitation
WBCs storage requirements?
24 hours at 20-24 deg C, without aggitation
FFP storage requirements?
1 year at -18 deg C
7 years at -65 deg C
24 hours at 1-6 deg C after thaw
Can be used as thawed plasma following that, low in factors 5 and 8
Cryoprecipitate storage requirements?
1 year at -18 deg C
4 hours (after pooling) at 20-24 deg C
RBC QC
Hct < 80% (all)
RBC leukoreduced QC
< or = 5 x 10^6 WBC in 95% and retain 85% RBCs
Platelets (PC) QC
> or = 5.5 x 10^10 and pH > or = 6.2 in 95%
Apheresis platelets QC
> or = 3 x 10^11 and pH > or = 6.2 in 90%
Apheresis platelets leukoreduced QC
<5.0 x 10^6 WBC in 95%
Cryoprecipitate QC
> or = 80 IU of Factor 8
> or = 150mg of Fibrinogen
Granulocyte concentrate QC
> or = 1 x 10^10 in 75%
Minimum irradiation dose
2500 cGys of gamma radiation
Storage requirements of RBCs following irradiation
28 days post irradiation or expiration date, whatever comes first
What platelets to use for NATP?
Washed maternal platelets due to maternal IgG against HPA-1A antigen (anti-PLA1) on fetal plts
Risk factors for TA-GVHD
Immunosuppression (Tcell deficiencies, Bone marrow tx, Fludaribine)
Intrauterine and premature infants
Hodgkins lymphoma + other heme malig
HLA matched product or 1st degree relative
Why used leukoreduced products?
Prevent HLA immunization
Prevent CMV transmission
Prevent febrile non-hemolytic reactions
Author
egoranson
ID
17771
Card Set
blood bank blood storage
Description
blood bank blood storage
Updated
2010-06-05T03:58:12Z
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