S4M2 pharm

ribavarin
- inhibitor of viral capping
- always given with INF-alpha
- HCV, RSV, viral pneumonia
INF alpha
- dec viral rep and inc IR
- activate JAK-STAT ic signalling
- HBC, HCV
Lamivudine
- NRTI
- HBV
- a/e: lactic acidosis, steatorrhea and nephrotox
Entecavir
- Nucleotide analog
- HBV (no food) **greatest efficacy of antiviral agts
- inhibition of vRT
Adefovir
- NT analogue = vRT inhibitor
- HBV, HIV, herpes (least likely to induce seroconversion)
- nephrotox, lactic acidosis, fatty liver
Telbivudine
- thymine NS analogue= vRT competative inhibiton
- HBV
- high viral res and rebound can occur after cessation

Author

sweetlu

177543

Card Set

S4M2 pharm

Description

S4M2 pharm

Updated

2012-10-14T14:47:07Z

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