Patho 3

Normal anion gap
- 5 - 11 mEq/L
- (8 mEq/L)
What are implications of high anion gap?
- Strongly suggests:
- = lactic acidosis (lactate)
- = ketoacidosis (BOH butyrate)
- = renal failure (sulfates, phosphates)
- = ingestion of certain poisons - salicylates (produce excess acid metabolites)
What is anion gap if HCO3- decreased and Cl- increased?
- Normal range = 5 - 11 mEq/L
- Examples:
- = gut (laxative abuse)
- = kidney disorders
Anion Gap formula
(Be able to calculate)

Anion Gap = [Na+] - [Cl-] + [HCO3-]
Osmolol Gap
- high osmolol gap = solutes present in plasma that are not normally there
- strongly suggests methanol or ethylene glycol intoxication (esp. if greater than 25 mOsmol/kg)

Author

cgordon05

17737

Card Set

Patho 3

Description

anion gap

Updated

2010-05-04T17:45:33Z

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