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Binary Fission
- The way that prokaryotes divide
- A single chromosome is replicatedm then as the plasma membrane and the cell itself elongates, the two chromosomes separate yielding 2 cells
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Mitosis
- Somatic Cells
- One duplication of genetic material, followed by one cell division, resulting in two identical daughter cells
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Meiosis
- Generates sex cells
- One duplication of genetic material, followed by two cell divisions, resulting in four different haploid cells containing half of the number of choromosomes of the parent cells
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Somatic Cells
Any biological cell forming the body of an organism; that is, in a multicellular organism
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Diploid Cell
A cell that contains two sets of chromosomes
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Haploid Cell
A cell that contains one complete set of chromosomes
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Chromosome Number
- Constant except for in sex cells, which posses half as many
- Constant among all individuals of a species
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Homologues
- Forms the basis of organization for comparative biology
- Organs as different as a bat's wing, a seal's flipper, a cat's paw and a human hand have a common underlying structure of bones and muscles
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Chromatin
The combination of DNA and proteins that make up the contents of the nucleus of a cell
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Nucleosome
The basic unit of DNA packaging in eukaryotes, consisting of a segment of DNA wound in sequence around four histone protein cores
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Histone Proteins
Highly alkaline proteins found in eukaryotic cell nuclei that package and order the DNA into structural units callednucleosomes
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Kinetochore
The protein structure on chromatids where the spindle fibers attach during cell division to pull sister chromatids apart
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Karyotype
The number and appearance of chromosomes in the nucleus of a eukaryotic cell
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Cell Cycle
The sequence of events that occurs in a cell from one cell division to the next
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Interphase
Not part of cell division, the new daughter cell has just emerged from a division, in time, it will grow and prepare for division
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Interphase (Gap 1)
A time of rapid growth, in which the cell doubles in size, cell is very metabilically active
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Interphase (S-Phase)
- Period of DNA synthesis
- DNA is replicated by the semi-conservative method
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Interphase (Gap 2)
Synthesis of spindle fibers and aster proteins-microtubules, enzymes, and structure needed for mitosis to occur
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M Phase (Prophase)
Chromatin super coils and condenses to form a propeller shaped chromosome
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M Phase (Prometaphase)
Kinetochores (a protein complex) develops on each side of the chromosome, at the centromere
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M Phase (Metaphase)
Chromosomes are lined up at the equatorial plate of the cell; highly organized appearance and easily recognized under the microscope
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M Phase (Anaphase)
Two sister chromatids of each duplicated chromosome separeate at the centromere (point of attachment), giving rise to 2 daughter chromosomes
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M Phase (Telophase)
Daughter cells reach their respective poles, a new nuclear envelope forms around daughter chromosomes
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Cytokineses
- Begins in Anaphase
- Continues in Telophase
- Ends in Interphase
- Is the division of the cytoplasm
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Daughter Cell
Cells that are genetically identical to the parent cell because they contain the same number and type of chromosomes
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Cell Plate
A disc like structure in the plane of the equator of the spindle that separates the two sets of chromosomes during cytokinesis; also involved in the formation of cell wall between the two daughter cells following cell division
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Cleavage Furrow
A constriction between the two daughter cells formed by the contractile ring
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Actin
Most abundant protein in the typical eukaryotic cell, accounting for about 15% in some cell types
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Centrosome
An organelle that serves as the main microtubule organizing center (MTOC) of the animal cell as well as a regulator of cell-cycle progression
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Centrioles
Cylindrically-shaped cell structure found in most eukaryotic cells, though it is absent in higher plants and most fungi
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Spindle (Fibers)
Extend from the cell poles toward the midpoint of the cell known as the metaphase plate
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Microtubules
A component of the cytoskeleton; these cylindrical polymers of tubulin can grow as long as 25 micrometers and are highly dynamic
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Centromere
Part of a chromosome that links sister chromatids; during mitosis, spindle fibers attach to the centromere via the kinetochore
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Chromatid
One of the two copies of DNA making up a duplicated chromosome, which are joined at their centromeres, for the process of cell division (mitosis or meiosis)
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Equitorial Plate/Metaphase Plate
The plane located midway between the poles of a dividing cell during the metaphase stage of mitosis or meiosis; it is formed from the migration of the chromosomes to the center of the spindle
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Telomere
A region of repetitive nucleotide sequences at each end of achromosome, which protects the end of the chromosome from deterioration or from fusion with neighboring chromosomes
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Euchromatin
A lightly packed form of chromatin (DNA, RNA and protein) that is rich in gene concentration, and is often (but not always) under active transcription
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Heterochromatin
A tightly packed form of DNA, which comes in different varieties
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Cyclins
A family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase enzymes
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Oncogene
A gene that has the potential to cause cancer, in tumor cells, they are often mutated or expressed at high levels
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Cancer
The disease caused by an uncontrolled division of abnormal cells in a part of the body
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Tumor
An abnormal growth of body tissue; they can be cancerous (malignant) or noncancerous (benign)
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Carcinogenesis
The initiation of Cancer formation
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Metastasis
The spread of a disease from one organ or part to another non-adjacent organ or part
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