Dosages

Dosage via IV/IO, IM, Sub-Q, SVN, or ETT

• Cardiac arrest, all rhythms (for dead people)
• Epi 1mg of 1:10,000 IV push with 20cc NS flush q 3-5 minutes, no limit          
• ETT route Epi 2mg of 1:1,000 diluted in syringe with 8cc

• Anaphylaxis, Refractory bronchospasm
• Epi 0.3mg of 1:1,000 IM

• Infusion for hypotension     
• Epi 1, 2, or 4mg 1:1,000 added to 250cc NS at 2-10mcg/min     
• Use after other treatment

All doses are VERY slow IV push over 2-5 minutes with the patient supine

Verapamil 2.5-5.0mg VERY slow IV push over 2-5 minutes.  May repeat in 15-30 minutes with 5-10mg

Cardiac: 325 (4 x 81mg pediatric chewable tabs), chew or swallow

• Peds
• Not indicated for prehospital

All dosage VERY rapid IV push over 1-3 seconds followed by 20cc NS flush with patient supine.  
     16 or 18 guage in the AC
     Use injection port closest to hub
     Have ECG printing during administration

Adult
6mg rapid IV push with 20cc NS flush.  May repeat twice every two minutes wtih 12 mg

IV push, ETT, or infusion
Adult - 
1.0 - 1.5mg/kg IV push
Every 5-10 minutes at 1/2 original dose up to 3mg/kg max

If successful - infusion at 2-4mg/min by adding 1gm to 250cc NS

Cardiac arrest - 20cc NS flush after giving
ETT dose - double IV dose

All Dosages are IV Push or ETT - FAST

Adult

Symptomatic Bradycardia
     Atrial mechanisms only
          Atropine 0.5mg IV Push - q 5 min - max 0.04mg/kg

Acetylcholinestrase inhibitor poisoning
Cholinergic poisoning
     Atropine 2.0 - 5.0 mg IV Push - q 5 min - until symptoms resolved

MOA depends upon dosage

Dopamine dose 1-2mcg/kg/min
     Activates dopamine receptors causing cerebral, renal, mesenteric vasodilation
          May increase urine output
          May drop BP

Beta-1 Dose 2-10mcg/kg/min
     Activates Beta-1 receptors stimulates heart increasing cardiac output & BP
          Postive inotrope
          Positive chronotrope
          Postivite dropmotrope

Alpha-1 dose 10-20mcg/kg/min
     Activates Alpha-1 receptors causing renal, mesenteric, & peripheral vasoconstriction
          Increases PVR increases BP
          Increased Preload
          >20mcg/kg/min similar to norepi with massive vasoconstriction

• All doses via IV infusion
• 
  Add 400mcg to 250cc NS bag giving 1600mcg/cc
       Symptomatic bradycardia with hypostension &/or non-hypovolemic shock
•           Dopamine 5mcg/kg/min initial infusion, increase if no repsonse

All hytpoglycemic doses are IM.  Other indications may be given IV.  

• Adult:
• Hypoglycemia
•      Glucagon 1mg IM
• Smooth muscle relaxant/Beta-blocker OD
•      Per agency or patch with medical control

All dosages via IV infusion or IM

• Adult
• Infusion
•      Pitocin 10 units added to 10000cc LR infused at rate necessary to control bleeding

• IM
•      10 units IM