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Function of the frontal lobe
- Motor: Primary motor area 4, secondary: motor area 6
- Volitional eye movements: Mediated by the frontal eye field, Saccadic eye movements depend on the integrity of this system
- Speech and language
- Motivational behaviour
- Working memory
- Attention
- Social behaviour
- Self awareness
- Self regulation
- Executive function
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Disturbances on motor function
- No voluntary movement/poor fractionalization of movement
- Abnormal muscle tone (spasticity)
- Release of primitive reflexes (grasp, suck, bite reflexes)
- Sphincter control
- Ventral prefrontal cortex – affective
- Dorsolateral prefrontal cortex – cognitive
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Disturbances to frontal lobe on volitional eye movements
Frontal lobe lesions can produce an alteration in voluntary eye gaze in relation to scanning the visual field appropriately
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Disturbances to frontal lobe on language
Expressive aphasia: the inability to perform the verbal expression of language. Non-fluent output
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Orbitofrontal cortex lesion
- Social convention
- Tend to have disinhibited, impulsive, inappropriate behaviour
- Poor social judgement
- Impulsive decision making
- Lack of consideration for impact of their behaviour
- Lack of empathy
- Apathy, disinterestedness
- Distractibility, restlessness
- Personal changes
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Ventral and polar motor cortex lesions
- Self regulation
- Damage to these areas may result in such significant changes that the person is not considered to be the same person
- Inability to regulate behaviour according to internal goals and constraints
- Lack of insight – lack of real understanding of problems and inability to act with one’s own interest in mind, despite knowing what to do and at least verbalising an intent to change
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Medial frontal motor cortex lesions
- Apathetic, indifferent
- Motor apathy: reduced gesturing, reduced verbal output, preservation
- Cognitive apathy: decreased curiosity, altered interest in learning, deducing and drawing logical conclusions, poor abstraction and categorization
- Affective apathy: diminished vocal inflection, reduced facial expression of internal emotional states
- Emotional apathy: reduced social interest, diminished affection, disinterest
- Motivational apathy: Reduced initiative
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Dorsolateral frontal cortex lesions
- Stategy formation and executive function
- Loss of mental flexibility
- Apathy
- Personality changes
- Aboulia
- Lack of ability to plan or sequence actions or tasks
- Poor working memory for verbal information (if left hemisphere) or spatial information (if right hemisphere)
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