T/F: Which of the following are true regarding atherosclerosis
is a specific disease
usually develops at bifurcation
is a segmental disease
is a generalized disease
intimal damage/repair may begin in adolescence
F,T,F,T
atherosclerois is a generalized disease that begins most often at bifurcations b/c of the shear forces generated at the wall surfaces. Px with atherosclerosis in the periphery will have other atherosclerotic changes in the carotid & coronary vesssels even though these may be clinically silent. Of all of the theories of its development, the injury/repair cycle seems to best account for the prevalence of coronary ather disease found on postmortem exam of young mell killed in Vietnam, Regardless of its etiology there is no quesiton that disruption of intimal continuity is the principal manisfestation