-
1. Cholestyramine- QUESTRAN
2. Colestipol- COLESTID
Types of bile-acid Sequestering agents
-
What do bile-sequestering agents do?
- Lower LDL
- Increase triglycerides
-
1. Fluvastatins- Lescol
2. Lovastatin- Mevacor
3. Pravstatin- Pravacho
l4. Simvastatin- Zocor
5. Atrovastatin- Lipitor
- HMG-CoA Reductase inhibitors
- aka "statins"
-
What do the HMG-CoA Reductase inhibitors do?
- Decrease LDL and Triglycerides
- Increase HDL
-
Which are the largest group of antihyperlipemics?
HMG-CoA Reductase Inhibitors
-
Which group of antihyperlipidemics requires frequent liver checks and why?
- HMG-CoA Reductase Inhibitors
- because they are most potent.
-
How is Questran administered?
Sprinkle on food
-
Which antihyperlipidemic is a type of B vitamin and what are the brand names?
Niacin (Nicotinic Acid, Nicobid)
-
What does vitamin B antihyperlipidemics do to LDL, Triglycerides and HDL?
- Decreases LDL and Triglycerides
- Increases HDL
-
If HMG-CoA Reductase Inhibitors are contraindicated what may be given instead?
Niacin
-
Which antihyperlipidemic increases glucose production and is contraindicated in patients with diabetes?
Niacin
-
1. Gemfibrozil- Lipid
2. Fenofibrate- Tricor
Fibric-Acid Deriviatives
-
What do fibric acid derivitives do to LDL, triglycerides, and HDL?
- Little to no effect on LDL
- Decrease Triglycerides
- Increase HDL
-
Which type of antihyperlipidemics are not to be given to patients with CAD?
Fibric-Acid Derivitives
-
Which type of antihyperlipidemic is used to prevent pancreatitis?
Fibric- Acid Derivitives
-
What is the new type of antihyperlipidemics and what is the drug name?
- Cholesterol Adsorption Inhibitor
- 1. Ezetimibe- Zetia
-
What does the new antihyperlipidemic do to LDL, etc?
- Decrease LDL, Triglycerides, Cholesterol
- Increases HDL
-
Which type of drug is enhanced when combined with statins?
Ezetimibe - Zetia
-
When is it recommended that a patient take antihyperlipidemics?
- LDL>190
- or
- LDL 160-190 with 2 or more risk factors
-
What inflammatory disorder does antihyperlipidemics help treat?
Athereosclerosis - lipid buildup in arteries
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