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Vortex keratopathy
-whorl-like epithelial deposits or opacitis in inferior epithelium caused by chloroquine and hydroxychloroquine (antimalarials) or amiodone (cardiac arrhythmia drug)
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Wilson Disease
-hepatolenticular dengeration leading to copper deposits in tissues (including cornea at peripheral part of descemt's: greenish Kayser-Fleischer ring)
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Dellen
- -localized corenal thinning or local dehydration of stroma
- -treat with lubricants, blinking exercises
- -severe: treat with bandage lens, patch
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Marginal Keratitis
- -hypersensitivity to staph. Exotoxins (chronic staph blepharitis)
- -treat with tobradex
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Roscaea keratitis
- -inferior punctate epithelial defects, marginal keratitis and neovasc, corneal thinning and perforation possible
- -treat: topical steriod (FML) antiobiotic ointment, lubricants
- -LT treat: tetracycline, doxycycline
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Phlyctenulosis
-hypersens rxn to bacterial antigen (esp. staph), white nodule in children
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Neuroparalytic (exposure) keratopathy
- -poor wetting of ocular surface (amd mild interior punctate to severe ulceration) due to facial nerve palsy
- -treat: lubricants, tape lids, surgery
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Vortex keratopathy
-def'n
-causes
- -whorl-like inferior epithelial deposits
- -antimalarial (chloroquine and hydroxychloroquine), amiodorone cardia arrhythmia drug
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Wilson disease
-def'n
-hepatolenticular degeneration leading to cooper deposition in tissues (ie. cornea at peripheral part of descemets membrane (Kayser-Fleischer ring))
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Mucopolysaccharidoses
-def'n
-Sxs
- -inherited deficiency in mucopolysaccharide metabolism (Hurler's Syndrome)
- -corneal depositis, skeletal anomalies, pigmentary retinopathy, ON atrophy (white, pale, grey)
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Arcus Senilis
-def'n
-affected
- -lipid deposits in stroma, not a concern
- ->50yrs old Pt
- -dislipidemia in younger Pt
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Vogt Limbal Girdle
-def'n
- -common, bilateral crescent shaped calcium depositis in nasal and temporal limbus
- -not a concern, age-related degeneration
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Cornea Guttata
-def'n
- -common, focal accumulation of collagen on posterior Descemts membrane
- (aka. Hassall-Henle bodies at periphery)
- -not significant, sign of aging
- -May be assocated with Fuchs dystrophy
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Band keratopathy
-def'n
-causes
-Mx
- -deposition of calcium salts in anterior portion of Bowmans membrane that DISRUPTS VISION
- -causes: chronic anterior uveitis, chronic severe keratitis, age, metabolic (elevated serum calcium), hereditary
- -Chelation (epithelium removed), excimer laser (PTK)
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