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- author "Dan"
- fileName "Psych 110 test 1"
- tags "Physio psychology"
- description "Neurons, brain anatomy"
- Physio psychology
- Relationship between brain and behavior
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Galen discovered
Nerves entered brain
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Descartes believed
Behavior was innate, dualism
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Locke believed
Tabula rasa
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Darwin characteristics have
Functional signficance. Adaptive behaviors are not inherited but the brain that carries out these behaviors are.
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Gall believed
Bumps on skull revealed mental functions, traits
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Consciousness
Hard problem, only know our own. Easy problem, can alter it
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Blind sight
Damage to visual cortex, relies on primative visual system
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Natural selection
If characteristic permit it to reproduce more successfully, characteristics become more prevalent in population
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Evolution
Gradual change in structure as a result of natural selection
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Human brain vs animal brain
Larger relative to body size, more neocortex
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Enzymes
Proteins that control rate of chemical reactions
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Mitocondria
Organelle which produces ATP from glucose for the cell
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Action potential
Abrupt depolarization of the membrane for a brief period of time that allows the neurons to cummunicate over long distances
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Membrane potential
The electrical charge across a cell membrane or the difference in the electrical potential inside and outside of the cell.
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Resting potential
The membrane potential of a neuron at rest, -70 mV
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Depolarization
Towards zero voltage
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Hyperpolarization
More negative voltage
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Threshold of excitation
Voltage level which triggers action potential, -60 mV
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Diffusion
Movement of molecules from regions of high concentration to regions of low concentration
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Electrolytes
Materials charged in water
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Sodium ion pump
Constantly operating, pumps 3 Na+ ions out and 1 K+ ion in to reset neuron for action potential firing
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Rate law
Intensity of firing rate
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Refractory period
Period where action potential cannot fire. Absolute vs. relative (relative is in hyper polarization)
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Saltatory conduction
Jumps from node of ranvier to node. Economy (less Na/K ion pumps), speed of signal
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Synapse
Space between terminal button and neuron
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Synaptic vesticles
Contains neurotransmitters. 1 vesticle released per AP via Ca++ions released from voltage dependent channel in terminal buttons
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Exocytosis
Process by which the vesticles release their content outside of the membrane by fusing with the membrane.
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Ligand
A chemical which binds to a binding site of a receptor. Binding forms higand-receptor complex which opens or closes ion channel
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Depolarization of soma
Influx of Na+ or Ca++ ions
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Hyper polarization
Efflux of K+ or influx or Cl- ions
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Post synaptic potentials
- Excitatory - increases chance of fire
- Inhibitory - decrease chance of fire
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Neural integration
- Spatial summation - summing of PSP at different synapse
- Temporal summaton - summing of PSP over time at same synapse
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LGC
Ligand Gate ion Channel or ionotropic receptor
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GPCR
- G Protein Coupled Receptor
- Reacts with enzymes to create second messenger which can:
- 1. Enter nucleus and affect gene transcription
- 2. Open ion channels
- 3. Change Ca++ levels
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PSP cleanup
- Reuptake - neurotransmitters taken back into terminal buttons
- Enzymic deactivation (Ach deactivated by AchE)
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Types of neurons
Motor, sensory, inter neurons
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Somatic nerves
Body senses
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Autonomic nerves
Heart rate, breathing
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Afferent nerves
Go inside CNS
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Neuron membrane is made of
Lipid bylayer
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Cytoplasm
Jelly like substance that fills the cell
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Mitocondria
Organelle which extracts energy from nutrients (ATP)
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Nucleus
Contains chromosomes, long strands of DNA
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Cytoskeleton
Proteins to give cell shape
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Enzymes
- Controls chemical reaction
- Metabolic - makes something
- Catabolic - breaks down
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Endoplasmic reticulum
Parallel layers of membranethat serves as storage and channel for transporting things through cell
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Axoplasmic transport
- Process by which substances are transported up down axon
- Anterograde - away from soma
- Retrograde - towards soma
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Glia
- 50% volume of CNS
- Provides physical and chemical buffers to isolate neurons
- Surrounds neurons in place
- Control supply of chemicals
- Insulate neurons from each other
- House keepers
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Astrocytes
- Physical support
- Clean up debris (phagocytosis)
- Aid in extra cellular chemical environment
- Provide nurishment
- Blood brain barrier
- Surround and isolate synapse
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Ogligodendrocytes
- Provide support to axons
- Provide myelin sheath
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Microglia
- Phagocytosis - breaks down dead and dying neurons
- Protects brain from microorganisms
- Inflammatory response to brain damage
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Schwann
- Myelin for PNS
- Single cell for one axon
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Blood brain barrier
- Semi permiable membrane produced by cells in the walls of the capillaries in the brain
- Regulates composition of extracellular fluid
- Selectively permeable
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Nuclei
Collection of cell bodies in CNS
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Ganglia
Collection of cell bodies in PNS
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Contralateral
Opposite side
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Meninges
- Protects the brain
- Dura mater - thick tough flexible outer layer
- Arachnoid membrane - spongy middle layer
- Pia mater - thin inner layer
- Sub arachnoid space - space between arachnoid membrane and pia mater filled with CSF (cerebral spinal fluid)
- PNS only has dura mater and pia mater
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Ventricular system
Cerebral Spinal Fluid flows from lateral into 3rd into cerebral aquaduct into 4th into sub arachnoid space then blood
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Frontal lobe
- Motor functions
- Inhibatory and planning
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Parietal lobe
Sensory functons
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Lateralization
Functions are located in just one cerebral hemisphere
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Contra lateralizaton
Right brain controls left side, etc
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Choroid plexus
Makes CSF from blood
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Corpus collosum
Connects left and right hemispheres
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Left brain
- Verbal
- Logic, analytic
- Interpretor
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Right brain
- Spatial
- Creativity, holistic
- Recognize emotion, facial expression
- Maintains accuracy
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Diencephalon
Thalamus, hypothalamus, pituitory gland
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Thalamus
- Relay to cortex
- Two lobes
- Many nuclei
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Hypothalamus
- Controls autonomic and endocrine system
- Fighting, fleeing, feeding, mating (4 F's)
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Pituatory gland
- Anterior - controls hormones, endocrine system
- Posterior - extension of hypothalamus
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Limbic system
- Emotion, learning, memory
- Hippocampus, amygdala, fornix, mammilary bodies, cingulate gyrus
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Hippocampus
Memory, learning
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Amygdala
Emotion, learning
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Fornix
Fiber tract connects hippocampus with mammilary bodies
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Mammilary bodies
Protrusion in base of brain
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Cingulate gyrus
Region of limbic cortex
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Basil ganglia
- Collection of nuclei involved in control of movement
- Caudate
- Putamin
- Globus pallidus
- Thalamus
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Pons
- Reticular formation (sleep, arousal)
- Relay nuclei cortex to cerebellum
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