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What system is responsible for returnign tissue fluid to the blood and for protecting the body against foreign material?
The Lymphatic system
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What are the parts of the Lymphatic system
- lymph
- lymph vessels
- lymphatic tissue: which includes lymph nodes, nodules, spleen, and thymus gland
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What is the tissue fluid that enters lymph capillaries
Lymph
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These are dead-end lymph capillaries found in most tissue spaces
Lymph vessels
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these are specialized lymph capillaries in the villi of the small intestine that absorb fat-soluble end products of digestion.
Lacteals
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Lymph vessels in the extremities, especially the legs are compressed by the skeletal muscles that surround them what is this called
the skeletal muscle pump
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What alternately expands and compresses the lymph vessels in the chest cavity and keeps the lymph moving
respiratory pump
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a vessel formed from lymph vessels from the lower body uniting in front of the lumbar vertebrae which this vessel continues upward in th front of the backbone as the thoracic duct.
cisterna chyli
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Lymphatic tissue consists mainly of what type of tissue
mainly lymphocytes in a mesh-like framework of conncective tissue
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The thymus has stem cells that produce a significant portion of which lymphocytes
T lymphocytes
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Lymph nodes and nodules are what type of tissue
lymphatic tissue
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these are encapusulated and are found in groups along the pathways of lymph vessesl and lymph flows through these on its way to the subclavian veins. they are about 10-20 mm in length
lymph nodes
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these are smaller masses of lymphatic tissue. smaller than the lymph nodes and have no capsules found just beneaththe epithelium of all mucous membrane
lymph nodules
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Plasma cells develop from which lymphocyte
B lymphocytes exposed to pathogens in the lymph and produce antibodies
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what are some names of lymph nodules
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The lymph nodules of the small intestine are called
Peyer's patches
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What is the important function of Peyer's patches
to learn to distinguish food (friend) to foe
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What organ is like a largy lymph node
the spleen
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what are the functions of the spleen
- has plasma cells that produce antibodies to foreign antigens
- phagocytize pathogen or ther foreign material in blood
- phagocytize old red blood cells and form bilifubin
- does clean up and repair
- stores platelets and destroy them when no longer needed
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what organ is located in the upper left quadant of the abdominal cavity, just below the diaphragm, behind the stomach
spleen
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what organ is located inferior to the thyroid gland
thymus
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what does the stem cells of the thymus produce
T lympocytes or T cells
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What are the two capabilities developed in the thymus from immature T cells
- self-recognition
- self-tolerance
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this is the ability to distinguish the cells that belong in the body from those that do not
self-recognition
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this is the ability not ot react to proteins and other organic molecules our cells produce
self-tolerance
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this is the ability to destroy pathogens or other foreign material and to prevent further cases of certain infectious diseases.
immunity
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these are chemical markers that identify cells
Antigens
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what are the two main components of immunity
- innate immunity
- adaptive immunity
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aka nonspecific, does not creat memory, response is always same regardless of target. has anatomic and physiological barriers, phogcytic and other defensive cells, and chemical secretions and reactions, including inflammation
innate immunity
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What cells are circulated in the blood but are also found in the red bone marrow, spleen, and lymph nodes and are able to destroy many kinds of pathogens and tumor cells
Natural killer cells
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these cells are defensive cells that are found throughout the areolar connective tissue of ucous membranes and the subcutaneous tissue and produce histamine and leukotrienes
Basophils and mast cells
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a chemical defense that are protein produced by cells infected with viruses and by t cells
interferons (Alpha-, beta-, and gamma-interferons)
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what are the 3 aspects of innate immunity
- barriers
- defensive cells
- chemical defenses
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what are the barriers from pathogens
- Integumentary system
- Mucous membranes and lysozyme
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What are the defensive cells from innate immunity
- Langerhans cells
- Phagocytes
- Natural killer cells
- Basophils and mast cells
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What are the chemical defenses of our innate immunity from pathogens
interferon (T cell blocks viral reproduction) complement (lyses cells attracts WBCs)inflammation
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is a chemical defense. is a group of more thanĀ 20 plasma proteins that circulate in the blood until activated. calls lysis of cellular antigens and labels of noncellular antigens.
complement
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this immunity is specific to its target, may involve antibodies, does create memory, and may become more efficient and is carried out by lymphocytes and macrophages
Adaptive immunity
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where are t cells produced
bone marrow and thymus
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When activated during an immune response these cells well divide many times and beome plasma cells that produce anibodies to a specific foreign antigen
b cells
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specialized groups of t lymphocytes are called
helper t cells
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this cell will remeber the specific foreign antigen and bcome active if it enters the body
memory T cells
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These cess are able to chemically destroy foreign antigens by disrupting cell membranes
cytotoxic T cells
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what is another name for antibodies
immune glogulins (Ig) or gamma globulins
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formed antigen-antibody comples which means the antigen is now labeled for phagocytosis by macrophages or neutrophils.
opsoniztion
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is the clumping of antibodies to bacterial cells
aggultination
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this type of immunity does not involve antibodies or immune system. it is the result of our genetic make up
genetic immunity
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this type of immunity requires antibodies
acquired immunity
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this immunity means that the antibodies are from another source (vaccines)
passive immunity
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This immunity means that the individual produces his or her own antibodies
active immunity
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What are the classes of antibodies
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crosses the placenta to provide passive immunity for newborns
provides long-term immunity following recovery or a vaccine
Location : blood, extracellular fluid
IgG
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present in breast milk to provide passive immunity for breast-fed infants
found in secretions of all mucous membranes
location: external secretions (tears, saliva,)
IgA
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Produced first by the maturing immune system of infants
produced first during an infection
Part of ABO blood group
Location: blood
IgM
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Receptors on B lymphocytes
Location: b lymphocytes
IgD
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Important in allergic reactions (mast cells release histamine)
location: mast cells or basophils
IgE
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