-
What is the normal pH range of blood
7.35-7.45
-
this means thickness or resistance to flow
viscosity
-
is the liquid part of blood and is approximately 91% of water
plasma
-
What is the most abundant plasma proteins
Albumin
-
is a plasma protein that are antibodies produced by lymphocytes
globulins
-
Blood cells are produced from stem cells in what tissue
hemopoietic tissue
-
After birth the hempoietic tissue is primarily what found in flat and irregular bones
red bone marrow
-
what is another way to measure the amount of RBC that invovles drawing blood into a thin glass tube called a capillary tube and centrifuging the tube to force all the cells to one end
hematocrit
-
Red blood cells contain what protein that gives them the ability to carry oxygen
hemoglobin
-
what are the precusor cells that are within red bone marrow
stem cells
-
the stem cells of the red bone marrow may also be called
hemocytoblasts
-
-
hormone produced by the kidney that stimulates the red bone marrow to increase the rate of RBC production
erythropoietin
-
this is the last stage with a nucleus, which then disintegrates
normoblast
-
what is another name for Vitamin B12
extrinsic factor
-
a chemical that combines with the Vitamin B12 in food to prevent is digestion and promote its absorption in the small intestine and is produced in the parietal cells of the stomach
intrinsic factor
-
A deficiency of either viatmin B12 or the intrinsic factor results in
pernicious anemia
-
what is the live span of RBC
120 days
-
what system removes the damaged cells from the circulation of cells
tissue macrophage system
-
The heme is convert to what by macrophages
bilirubin
-
first clump of RBC
agglutination
-
-
What is a normal WBC count
5000-10000 per uL
-
what are the 5 types of WBC
- neutrophils
- eosinophils
- basophils
- lymphocytes
- monocytes
-
the granular leukocytes are
- neutorphils
- eosinophils
- basophils
-
the agranular leukocytes are
-
which leukocytes are capable of the phagocytosis of pathogens
neutrophils and monocytes
-
During an infection, neutorphils are produced more rapidly and the immature forms are called
band cells
-
phagocytized dead or damaged tissue at the site of any injury, helpin to make tissue repair possible is
macrophages
-
is an anticoagulant that helps prevent abnormal clotting within blood vessels
heparin
-
part of inflammation process, and it makes capillaries more permeable allowing tissue fluid, protein, and WBC to accumulate in the damaged area
histamine
-
what are the two major lymphocytes
T cells and B cells
-
this cell helps recognize foreign antigens and may directly destory some foreign antigens
T cells
-
this cell becomes plasma cells that produce antibodies to foreign antigens
b cells
-
what cells destroy foreign cells by chemically rupturing their membranes
natural killer cells (NK cells)
-
A high WBC count is called
leukocytosis
-
A low WBC count is called
leukopenia
-
what is the formal name for platelets which are not whole cells but rather framents or pieces of cells
thrombocytes
-
large cells which break up into small pieces thatenter circulation
megakaryocytes
-
a hormone produced by the liver that increases the rate of platelet production
thrombopoietin
-
low platelet count
thrombocytopenia
-
prevention of blood loss
hemostasis
-
zipper-like glycoproteins that tend to come apart.
cadherins
-
when a large vessel such as an artery or vein is severed, the smooth muscle in its wall contracts in response to the damage.
myogenic response
-
the clot itself is made of a thread-like protein
fibrin
-
Once the clot has formed and bleeding has stopped what occurs
clot retraction and fibrinolysis
-
The liver produces a globulin that combines with an inactivates excess thrombin
antithrombin
-
clotting in an intact vessel; the clot itself is called
thrombus
-
a clot or other tissue transported from elsewhere that lodges in and obstructs avessel is called
embolism
-
what is the general function of blood
- transportation
- regulation
- protection
-
Plasma transports
- nutrients
- wastes
- hormones
- heat
- antibodies
- CO2 as HCO3
-
Plasma proteins are synthesized by what organ
liver
-
what protein is synthesized by liver and provides colloid osmotic pressure that pulls tissue fluid into capillaries to maintain normal blood volume and blood pressure
albumin
-
what protein is synthesized bny the liver and are carriers for fats and other substances in the blood
alpha and bet globulins
-
these are antibodies produced by lymphocytes
gamma globulins
-
what are the 3 formed elements
-
After birth what is the primary hemopoietic tissue
red bone marrow
-
after birth the hemopoietic tissue, red bone marrow contains what type of cell
stem cells
-
Lymphocytes mature and divide in to what
- lymphatic tissue of the spleen
- lymph nodes
- thymus
-
Biconcave discs with no nuclei when mature
Red Blood cells
-
RBC carry what type of gas and are bonded to what
O2 bonded to iron in hemoglobin
-
where are RBC formed in
Red Bone Marrow from hemocytoblasts
-
what stimulates the kidneys to produce the hormone erythopoietin, which increases the rate of RBC produciton in the RBM
Hypoxia
-
Immature RBCs
- normoblasts ( have nuclei)
- reticulocytes
-
large numbers in peripheral circulation indicate a need for more RBCs to do what
carry oxygen
-
What is the extrinsic factor needed for DNA synthesis (mitosis) in stem cells in the RBM
Vitamin B12
-
The intrinsic factor is produced by
parietal cells of the stomach lining
-
Larger than RBC and have nuclei when mature
WBC (leukocyte)
-
which WBC phagocytize pathogens
neutrophils and monocytes
-
monocytes become
macrophages also phagocytize dead tissue
-
which WBC detoxify foreign proteins during allergeic reactions and parasitic infections
eosinophils
-
which WBC phagoctyize anything labeled with antibodies
eosinophils
-
which WBC contain the anticoagulant heparin and histamine, which contributes to inflammation
basophils
-
what are the 3 lymphocytes
- T cells,
- B cells
- natural killer cells
-
which cell recognize foreign antigens and destroy them
t cells
-
which cell become plasma cells which produce antibodies to foreign antigens
b cells
-
whic cell destroy foreign cell membranes
natural killer cells
-
this is formed in the RBM and are fragments of megakaryocytes
Platelets
-
which hormone from the liver increases platelet production
thrombopoietin
-
what does platelets help maintain
endothelium of blood vessels
-
platelets also help prevent
blood loss
|
|