Micro 1

  1. What problems is Pseudomonas aeruginosa associated with?
    • wound and burn infection
    • Pneumonia (cystic fibrosis)
    • Sepsis(black lesions on skin)
    • External otitis (swimmers ear)
    • UTI
    • Drug use
    • Diabetic osteomyelitis
    • hot tub folliculitis
  2. What is Pseudomonas aeruginosa?
    • Aerobic gram negative rod
    • non-lactose fermenting
    • oxidase positive
    • produces pyocyanin pigment
  3. What is the treatment for Pseudomonas aeruginosa?
    aminoglycoside and extended-spectrum penicillin (piperacillin, ticarcillin)
  4. EIEC
    • Produces Shiga-like toxin
    • Microbe invades intestinal mucosa and toxin causes necrosis and inflammation.

    -> Invasive dysentery
  5. Salmonella
    • Gram negative non-lactose fermenters
    • have flagella and disseminate hematogenously
    • Produces H2S
    • antibiotics prolong symptoms

    Less virulent than Shigella

    Animal reservoir except S. typhi
  6. Weils Disease
    • Leptospira interrogans
    • - question mark-shaped bacteria found in water contaminated with animal urine

    Severe form with jaundice and azotemia from liver and kidney dysfucnction; fever, hemorrhage, and anemia.
  7. Borrelia burgdorferi
    Transmitted by Ixodes tick

    • Stage 1:
    • - erythema chronicum migrans (expanding "bull's eye red rash with central clearing)
    • - flulike symptoms

    • Stage 2:
    • - neurologic (Bells palsy, peripheral neuropathy)
    • - cardiac (AV nodal block and perimyocarditis)

    • Stage 3:
    • - chronic monoarthritis
    • - mgratory polyarthritis
    • - subacute encephalitis
  8. Pasteurella multiocida
    Zoonotic bacteria

    Causes Cellulitis and osteomyelitis

    • Transmission:
    • Animal bite; cats, dogs
  9. Rickettsia ricketsii
    • Transmitted by tick
    • Causes Rocky mountain spotted fever

    Symptoms: rash on palms and soles (migrates to wrists, ankles, then trunk), headache, fever

    Treatment : doxycycline
  10. Rickttsia typhi
    • Transmitted by flea
    • Causes Endemic typhus

    Symptoms: rash starts at trunk and spreads outward without involving palms or soles

    Treatment : doxycycline
  11. Coxiella burnetti
    • A rickettsial disease
    • Transmitted by spores of tick feces and cattle placenta that is inhaled

    No fever, negative Weil Felix reaction

    Causes Q fever (no rash), atypical pneumonia  

    Treatment: doxycycline
  12. Mycoplasma Pneumonia
    • Walking pneuomiae
    • Cross reacton of IgM to RBC
    • Tx: tetracycline and erythromycin
Card Set
Micro 1
Micro 1