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What problems is Pseudomonas aeruginosa associated with?
- wound and burn infection
- Pneumonia (cystic fibrosis)
- Sepsis(black lesions on skin)
- External otitis (swimmers ear)
- UTI
- Drug use
- Diabetic osteomyelitis
- hot tub folliculitis
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What is Pseudomonas aeruginosa?
- Aerobic gram negative rod
- non-lactose fermenting
- oxidase positive
- produces pyocyanin pigment
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What is the treatment for Pseudomonas aeruginosa?
aminoglycoside and extended-spectrum penicillin (piperacillin, ticarcillin)
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EIEC
- Produces Shiga-like toxin
- Microbe invades intestinal mucosa and toxin causes necrosis and inflammation.
-> Invasive dysentery
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Salmonella
- Gram negative non-lactose fermenters
- have flagella and disseminate hematogenously
- Produces H2S
- antibiotics prolong symptoms
Less virulent than Shigella
Animal reservoir except S. typhi
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Weils Disease
- Leptospira interrogans
- - question mark-shaped bacteria found in water contaminated with animal urine
Severe form with jaundice and azotemia from liver and kidney dysfucnction; fever, hemorrhage, and anemia.
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Borrelia burgdorferi
Transmitted by Ixodes tick
- Stage 1:
- - erythema chronicum migrans (expanding "bull's eye red rash with central clearing)
- - flulike symptoms
- Stage 2:
- - neurologic (Bells palsy, peripheral neuropathy)
- - cardiac (AV nodal block and perimyocarditis)
- Stage 3:
- - chronic monoarthritis
- - mgratory polyarthritis
- - subacute encephalitis
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Pasteurella multiocida
Zoonotic bacteria
Causes Cellulitis and osteomyelitis
- Transmission:
- Animal bite; cats, dogs
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Rickettsia ricketsii
- Transmitted by tick
- Causes Rocky mountain spotted fever
Symptoms: rash on palms and soles (migrates to wrists, ankles, then trunk), headache, fever
Treatment : doxycycline
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Rickttsia typhi
- Transmitted by flea
- Causes Endemic typhus
Symptoms: rash starts at trunk and spreads outward without involving palms or soles
Treatment : doxycycline
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Coxiella burnetti
- A rickettsial disease
- Transmitted by spores of tick feces and cattle placenta that is inhaled
No fever, negative Weil Felix reaction
Causes Q fever (no rash), atypical pneumonia
Treatment: doxycycline
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Mycoplasma Pneumonia
- Walking pneuomiae
- Cross reacton of IgM to RBC
- Tx: tetracycline and erythromycin
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