TMP/SMX (used for patients with beta-lactam allergies)
A 3-day old infant has contracted bacterial meningitis. How should you treat this infant?
D. ampicillin + gentamycin
What are the 3 most common causative agents for bacterial meningitis in an infant that is less than 1 month old?
S. agalactiae (GBS)
A 6-month old infant presents with a fever, irritability, poor feeding and a bulging fontanel. You suspect bacterial meningitis. What is your first-line of treatment?
D. vancomycin + ceftriaxone
What are the 3 most common causative agents for bacterial meningitis in persons 1 to 23 months of age?
S. agalactiae (GBS)
A 21-year old college student presents with a fever, stiff neck, mental status change and a petechial rash. He is later diagnosed with bacterial meningitis. What is the best drug treatment for this patient?
B. dexamethasone + vancomycin + ceftriaxone
What is the rationale behind giving a patient with bacterial meningitis a corticosteroid prior to the first antibiotic dose?
decrease inflammation in subarachnoid space caused by immunological response to lysis of bacteria
A 62-year old man has developed bacterial meningtitis. He has a fever, stiff neck, mental status change, but no rash, and he does not have a history of dementia or Alzheimer's disease. His wife tells you that he has a penicillin allergy. What is the best treatment for him?
In what age group is a bacterial meningitis infection caused by Listeria monocytogenes the most likely? What is the drug of choice to fight this infection?
<1 month old
>50 years old
The use of _____ to treat bacterial meningitis in neonates should be avoided.
What is the best drug treatment for prophylaxis of bacterial meningitis that is caused by N. meningitidis?
B. ciprofloxacin in 1 dose
An HIV-patient comes in your office and presents with a headache, fever, neck stiffness and photophobia. You suspect bacterial meningitis caused by Cryptococcus neoformans. How would you go about treating this patient?
A. amphotericin B + flucytosine for 2 weeks then fluconazole for 8 weeks
True or false. The vast majority of acute bronchitis infections are bacterial.
False, the vast majority of acute bronchitis infections are viral.
What are the 3 best treatment options for Pertussis (Whooping cough)?
macrolides (azithromycin - "Z-pack")
True or false. Influenza is easily treated with antivirals.
False, antivirals have minimal efficacy. Vaccines are key.
What are the 5 most common pathogens associated with COPD exacerbation?
A 52-year old woman comes into your office presenting with a mild case of COPD exacerbation most likely caused by S. pneumoniae. How would you treat her?
A 16-year old boy comes into your office complaining of a high fever, purulent nasal discharge and facial pain that has persisted for more than 4 days. You suspect bacterial sinusitis. How would you treat him?
C. amoxicillin/clavulanic acid
"The Big 6" pathogens that are most commonly involved in community-acquired bacterial pneumonia are:
How would you treat a community-acquired pneumonia out-patient who is previously healthy and has no risk for drug-resistance?
An immunosuppressed patient presents with community-acquired pneumonia that is caused by S. pneumoniae. They do not have any known drug allergies and are not resistant to any drugs. What is the best outpatient therapy for this patient?
B. penicillin + azithromycin
How would you treat a community-acquired pneumonia in-patient who is in the ICU with a concern for MRSA?