-
general penicillin
- benzyl penicillin G, penicillin V
- gram positive cocci = strept/staph
- gram negative cocci = neiserria menin/gonor
- gram positive bacilli = diptheria
-
anti-staphlococcal penicillin
- flucoxacillin
- staph aureus (G+ cocci)
-
anti-pseudomonal penicillin
- ticarcillin
- pseudomonas spp (G- bacillus - EXCEPTION)
-
extended spectrum penicillin
- ampicillin, amoxycillin
- gram +/- cocci
- gram + bacilli
- AND E.coli, H. pylori (G- bacilli - EXCEPTION)
-
1G cephalosporin
- cephazolin, cephalexin
- G- bacilli - PEcK
- Psuedomonas spp
- E.coli
- Kleibsella
-
2G cephalosporin
- cefuroxime, cefoxitin, cefotetan
- G- bacilli - HENPEck AND anaerobes
- H. influenzae
- Enterobactericeae
- Neisseria (cocci)
- e.g. community-acquired pneumonia
-
3G cephalosporin
- ceftriaxone
- same spectrum as 2G except can cross BBB
- indicated for meningitis
- peritonitis?
-
4G cephalosporin
- cefepime
- broad spec including both G+/-
- reserved for severe infections
-
non-beta-lactam cell wall inhibitor
- vancomycin (glycopeptide)
- MRSA
- Clostridium difficile
-
aminoglycoside
- gentamicin, tobramycin
- G- bacilli - HEPEcK
- H. influenzae
- Enterobactericeae
- Pseudomonas spp
- E.coli
- Kleibsella
-
tetracyclin
- doxycycline
- parasitic infections - G-bacilli MPC
- malaria (Plasmodium falciparum)
- plague (Yersinia)
- cholera (V. cholera)
-
macrolide
- erythromycin, roxithromycin
- similar to penicillin (G+) e.g. strept
- AND atypical pneumonia - MCL
- mycoplasma tuberculosis
- chylamidia spp
- legionella spp
- AND pertussis
- AND campylobacter
-
chloramphenicol
- G+/- cocci
- anaerobes e.g. Clostridium perfringes (gas gangrene)
-
rifampicin
- G+ cocci e.g. staph - infection of joint prostheses
- G- e.g. H. influenzae, Neisseria
- M. tuberculosis
-
fluoroquinolone
- ciprofloxacin, moxifloxacin (RTI)
- G- HENPEcK
- H. influenzae
- Enterobactericeae
- Neisseria
- Pseudomonas
- E. coli
- Kleibsella
- CF acute exacerbations - pseudomonas
-
metronidazole
- anaerobes
- e.g. Clostridium spp
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