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Megakaryoblast
- rarely recognized
- large cell
- single nucleus
- deep basophilic cytoplasm
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Promegakaryocyte
- large cell
- contains 2 - 4 separate or fused nuclei
- basophilic cytoplasm
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Megakaryocyte
- Gigantic cell
- multiple nuclei joined in a lobed mass
- cytoplasm may be basophilic or violet
- acidophilic cytoplasmic granules may be present
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Plasma cell
- approx. same size or slightly larger than mature neutrophil
- round, eccentric nucleus with coarse chromatin
- pale perinuclear clear zone may be present
- large amount of basophilic cytoplasm
- rarely contain round cytoplasmic structures (russell bodies)
- If russell bodies exist then it is a Mott Cell
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Osteoblast
- large cell, few seen
- may resemble plasma cell except larger and less condensed chromatin
- eccentric round to oval nucleus
- nucleoli may be present
- foamy basophlic cytoplasm
- perinuclear clear zone may be present
-
Osteoclast
- giant cell
- multinucleated, nuclei are distinctly separate
- blue cytoplasm
- cytoplasmic granules
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