Home
Flashcards
Preview
pain meds 1
Home
Get App
Take Quiz
Create
What is pain?
a common symptom subjective experience
defense mechanism
Pain theory
tissue damage activates the free nerve ending (pain receptors or nocieptors) of peripheral nerves
Chronic Pain
lasts longer than 6 months
Pain is the _______ vital sign
5th
Joint Commission on the Accreditation of Healthcare Organizations (JCAHO)
emphasizes importance of pain and it's management for all patients
Assessment of Pain
Patient's own perception numerical scale for uniformity
Use what to assess for pain?
quality duration onset intensity
Acute Pain
usually from injury to recovery for a defined period of time, usually less than 6 months
Chronic Pain
lasts longer than 6 months
Non-Pharmacological Pain Management
acupuncture biofeedback massage heat/cold relaxation chiropractics hypnosis music therapy
Alagesics
medications to relieve pain
2 main classes of medication
1. NSAIDS
2. Narcotic
NSAIDS
non-steroidal anti-inflammatory drugs aka non-opioids
How do NSAIDS work?
act at the peripheral level
Narcotic
Opioid analgesics
How do Opioids work?
act in the CNS
Opiates "or ""Opium"
milky extract of unripe sees of the poppy plant
How do opiates or opium work?
act like morphine in the body
"Natural ""morphine-like"" substance"
Synthetic Opioids
Narcotic- morphine like drugs - produces analgesia - produces CNS depression - can be Natural - morphine - can be synthetic - meperidine (Demerol)
Opioids narcotic substances
How do opioids work?
produce numbness or stupor-like symptoms
Opioids interact with what?
at least 6 receptor type cells
Opioids focus on what?
mu and kappa receptors
Opioids are
angonists/antagonists
what is the desired response for opioids?
Analgesia
Opioids are a scheduled ___ drug
II, highly abusive
Opioids analgesics reduces
severe pain
Opioids produce what type of symptoms?
numbness or stupor-like symptoms
How do opioids produce numbness?
inhibits production of pain and inflammation by prostaglandins in peripheral tissues
Therapueutic actions of opioid analgesics
- widespread pharmacologic effects especially in CNS and GI systems - Produces analgesia
Opioid Analgesics act mostly on ?
CNS
Opioid Analgesics inhibits transmission of pain signals from...
peripheral tissues to the brain
how does opioid anagesics produce analgesia
- reduces perception of pain - causes CNS depression - drowsiness-sleep-unconscious - decreases physical and mental activity
Opioid Agents Mechanism of Action
Binds to opioid receptors in brain and spinal cord
powerful CNA depressant
Powerful CNS depressant
- cause sedation - euphoria - intense relaxation - highly abusive
Opioids Pharmacokinectics
- IV administration most reliable to achieve therapeutic levels 100% bioavailability
opioid are better absorbed with what administration?
IM, oral, subq
opioids are absorbed faster in male or female?
Male
other routes of opioids?
epidural, intrathecally (directly into spinal column)
oral drugs undergo significant
"first-pass" metabolism
which form of opioids require increased dosages?
Oral
opioid metabolites are excreted in the
urine
Opioid is DOC for what symptom?
severe pain
morphine is the prototype drug for?
severe pain
Do opioids lower pain thresholds
No
Do opioids block transmission of pain?
no
what is the pharmocology of opioids?
alters the perception and emotional reponse to pain.
Reason opioids are abused?
produces euphoria and intense relaxation
Clinical Indications for opioids
Prevent or relieve acute or chronic pain
what are other uses for opioids other than pain relief?
- suppresses cough reflex center (Codeine) - slows motility of GI tract in severe diarrhea (Paragoric)
Adverse Reactions of Opioids
- Potentially life threatening - Respiratory Depression - Sedation/Somulence - Nausea/Vomiting/Constipation - Orthostatic Hypotension
Respiratory Depression in opioids
activation of the "mu" receptors in CNS mu receptors are primarily pain blocking receptors most serious adverse effect of this class of drug
why do opioids have the potential for physical/psychological dependence?
more likely to occur with higher doses for extended periods
Who is more likely to undermedicate?
healthcare workers
what happens when patients under-medicate?
energy expended in coping with pain pain management = increased healing time
Opioids Contraindications & cautions
respiratory depression COPD Liver disease renal disease BPH (urinary retention) increased ICP allergy
Author
jean
ID
17004
Card Set
pain meds 1
Description
pain meds 1
Updated
2010-05-03T14:48:22Z
Show Answers
Home
Flashcards
Preview