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MED-Lidocaine
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Functional Class
Class IB Antidysrhythmic (Sodium Channel Blocker)
Mechanism of Action
Suppresses depolarization and automaticity of His-Purkinje system
Suppresses ventricular ectopy
Increases threshold for ventricular dysrhythmias
However, d
ecrases ventricular threshold for fibrillation
Indications
VF
Pulseless VT
VT with pulse
Malignant PVCs
-More than six unifocal PVCs/minute
-Multifocal PVCs
-Couplets
-R-on-T phenomena
Contraindications
Hypersensitivity
Supraventricular dysrhythmias
Untreated sinus bradycardia
2nd Degree Mobitz II AV block
3rd Degree AV Block
Stokes-Adams Syndrome
Precautions
CNS depression may occur in doses over 300 mg/hour
Liver or renal disease
CHF
Hypovolemia
Shock
Mysthenia gravis
Side Effects
AMS
Confusion
Bradycardias
Hypotension
Seizures
Interactions
Use caution with Beta Blockers and Procainamide-drug toxicity may result
Dosage/Route
ADULT CARDIAC ARREST
1-1.5 mg/kg IVP repeat at half dose q 5 mins max total dose of 3 mg/kg
NOTE
: single dose of 1.5 mg/kg acceptable if moving on to Amiodarone
2-4 mg/kg ET q 3-5 mins
PEDIATRIC CARDIAC ARREST
1 mg/kg IVP/IO/ET
ADULT WITH PULSE
1-1.5 mg/kg IVP repeat at half dose q 5-10 mins max total 3 mg/kg
ADULT IV INFUSION
1-4 mg/min
Pharmacokinetics
Absorption
: 3 mins
Duration
: 10-20 hours
Half-life
: 1.5-2 hours
Author
amerelman
ID
16931
Card Set
MED-Lidocaine
Description
MED-Lidocaine
Updated
2010-04-30T14:29:03Z
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