Therio Q1/III

  1. What are the uses of FSH in vet med?
    stimulate ovarian function, superovulation for embryo transfer, promote spermatogenesis
  2. What are the uses of FSH in human medicine?
    assisted reproduction (superovulation) and polycystic ovary syndrome
  3. What type of molecule is LH?
  4. The release of LH is inhibited by what?
    low concentrations of P and E
  5. The release of LH is stimulated by what?
    estrogen spike
  6. What is the function of LH?
    binds to receptors on follicles, CL, and leydig cells ; stimulated progesterone production, testosterone production, and ovulation ; activates pre-ovulatory oocyte ; involved in puberty and seasonal cycles
  7. What are the uses of LH in vet med?
    induce ovulation in mares, treat cystic ovarain disorder in cows
  8. What produces a gonadotropin with LH activity in the pregnant mare, known as Equine Chorionic Gonadotropin or eCG?
    equine placenta
  9. What is the basis of pregnancy diagnosis in the mare?
    test for eCG
  10. What hormone acts during equine pregnancy to stimulate luteinization of follicles, maintain CL activity, or promote the production of estrogens?
    Equine chorionic gonadotropin
  11. eCG has LH like activity in what animal, and FSH like activity in other animals?
  12. How is eCG applied in vet med?
    produce postpartum anestrus in pigs, induction of puberty, increase ovulation rate in small ruminants, induce estrus in dogs and exotic mammals, superovulation in cattle
  13. What produces a gonadotropin with FSH and LH activity, called the human chorionic gonadotropin or hCG?
    human placenta
  14. What acts during human pregnancy to maintain CL activity or promote the production of progestins?
  15. How is hCG used in vet med?
    for timed ovulation in mares and to treat cystic ovarian disease in cows
  16. The LH/hCGB gene cluster consists of what?
    one LHB gene and six hCGB genes
  17. Why is repeated use in the same animal of hCG not indicated?
    reduced effecitveness with the later administrations, has the potential to trigger reactions with consistent use
  18. What are 3 things that need to be kept in consideration when dealing with FSH, LH, hCG, and eCG?
    1. will degrade rapidly if kept at room temp, 2. capable of generating an immune response (from repeated use), 3. b/c derived from animal tissue, purity of preparation is in question
  19. Which dog breed is the only one that has a single annual seasonal ovulation?
  20. In the bitch, the beginning of anestrus is marked by what?
    P4 returning to basal levels
  21. In the bitch, the end of anestrus is marked by what?
    bloody vaginal discharge on the first day or proestrus
  22. What phase in the bitch is defined endocrinologically as P4 less than 1-2 ng/ml, and is the quiescent phase of cycle behaviorly and clinically?
  23. How long does anestrus usually last in the bitch?
    4-5 months
  24. How often does estrus usually occur in the bitch?
    slightly less than twice annually
  25. An interval of less than 4 months of interestrus in the bitch tends to result in what, and why?
    infertility, because the endometrium needs time after luteal phase for repair
  26. Why is prolactin possibly important to maintaining the length of estrus in the bitch?
    suppression of prolactin with bromocriptine shortens estrus, as well as cabergoline (prolactin inhibitor)
  27. What is the average duration of proestrus in the bitch?
    9 days
  28. What stage in the bitch is defined by blood passing from swollen vulva, may attract males, but not receptive to mating, there is an increasing percentage of "superficial" cells?
  29. What is the average duration of estrus in the bitch?
    9 days
  30. In the bitch, what is often used to define the first day of estrus endocrinologically?
    LH peak
  31. What is the cytological definition of estrus in the bitch?
    superficial cells > 90% (cornification)
  32. How long does ovulation occur after the LH surge in the bitch?
    2-3 days
  33. Fertilization takes place how long after ovulation in the bitch?
    48-72 hours (after the first meiotic division), 5-6 days after onset of estrus
  34. When does vaginal cytology change to parabasal in the bitch?
    8-9 days after LH (fertility low when mated at this time)
  35. How long is the length of diestrus in the bitch?
    approx the length of gestation
  36. When does galactorrhea commonly occur in the bitch?
    at the end of luteal phase
Card Set
Therio Q1/III
Therio Q1/III