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Toxicology Thrapeutic Drugs and Ranges

  1. What is the therapeutic range for Theophylline? what is the toxic range for theophylline?
    Therapeutic: 10 - 20 ug/mL

    Toxic: >25 ug/mL
  2. What are the effects of Theophylline?
    Muscle Relaxant.

    Stimulates CNS; Increases respiratory rate
  3. what is the therapeutic range for Digoxin, and when does it become toxic?
    Therapeutic: 0.8 - 2.0 g/mL

    Toxic: >3.0 g/mL
  4. what are the effects of Digoxin?
    Improve cardiac contractions in CHF
  5. what is the therapeutic dose for Lidocaine and when does it become toxic?
    Therapeutic: 1.5 - 5.0 ug/mL

    Toxic: >5 ug/mL
  6. what are the effects of Lidocaine?
    Correct ventricular arrhythmias
  7. what is the therapeutic dose for Phenobarbital and when does it become toxic?
    therapeutic: 15 - 40 ug/mL

    toxic: N/A
  8. what are the effects of Phenobarbitol?
    treats febrile seizures and neonatal seizures
  9. what is the therapeutic dose for valpruic acid and when does it become toxic?
    therapeutic: 50 - 100 ug/mL

    toxic: > 100 ug/mL
  10. effects of valpruic acid
    treatment for petit mal and myclone seizures
  11. what is the therapeutic range for Chloramphenicol and when does it become toxic?
    therapeutic: 10 - 20 ug/mL

    toxic: >25 ug/mL
  12. what are the effects of Chloramphenicol?
    multi purpose antibiotic (primarily aplastic anemia)
  13. what is the therapeutic range for vancomycin and when does it become toxic?
    therapeutic: trough (5 - 10 ug/mL) peak (30 - 40)

    toxic: trough (>20) Peak (>80)
  14. what are the effects of Vancomycin?
    antibiotic against GPC and GPR
  15. what is the therapeutic dose for Cholinesterase and when does it become toxic?
    • therapeutic: 4,000 - 12,000
    • toxic: N/A
  16. what are the effects of cholinesterase
    secondary to insectiside exposure; insecticide poisoning
  17. what is the therapeutic dose for Salicytate and when does it become toxic?
    therapeutic: <30 mg/dL

    toxic: >30 mg/dL
  18. what are the effects of Salicytate?
    analgestic (respiratory acidosis)
  19. what is the therapeutic dose for acetaminophen and when does it become toxic?
    therapeutic: 10 - 25 mg/dL

    toxic: 100 - 250 mg/dL
  20. what are the effects of acetaminophen?
    delays toxicity due to liver necrosis 3 - 4 days post
Author
Rabidplatypus
ID
16806
Card Set
Toxicology Thrapeutic Drugs and Ranges
Description
Ranges, MLT
Updated

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