Protein structure (1-4)

  1. 1 (Primary)

    • -the sequence of amino acids (ala thr set tyr his gly)
    • -the N-C-C backbone
    • -the level held together entirely by strong forces
    • -the strand that indicated the path of the bonded chains
  2. 2 (Secondary)

    • -beta-sheet
    • -held together by repeating patterns of hydrogen bonds which are roughly perpendicular to the chain axis
    • -alpha-helix
    • -regularly placed hydrogen bonds within the same chain (perpendic intramolecular h-bonds)
    • -regular patterns that show up clearly in x-ray crystallographic analysis
  3. 3 (Tertiary)
    • -may have some disulfide covalent bonds as cross-links
    • -mainly caused by proline, charge attractions, charge repulsions, and weak forces
    • -the way the polypeptide chain is folded to form a compact globular structure
    • -the level of protein structure most responsible for the lock-and0key mechanism of enzymes
    • -oil dropo model describes the force that cause this level
    • -domains, which show 3d homology to comparable proteins in related species
    • -has bits of "irregular structure" or "random chain" and "bend regions"
  4. 4 (Quaternary)
    • -association of clustering of several globular units
    • -the level of structre that myoglobin doesnt have
    • -supramolecular aggregation
Card Set
Protein structure (1-4)