Common Biological Response Modifiers

  1. Sangramostim (Leukine, Prokine)
    Chemotherapy-Induced leukopenia
  2. Filgrastim (Neupogen)
    Neutrophils (neutropenia)
  3. Pegfilgrastim (Neulasta)
    Neutrophils (neutropenia)
  4. Epoetin alfa (Epogen, Procrit)
    Erythrocytes (anemia)
  5. Oprelvekin (Neumega)
    Platelets (thrombocytopenia)
  6. Interleukins (IL-1 IL-2, IL-6)
    Help different immune system cells recognize and destroy abnormal cells.  Appear to charge up the immune system and enhance attacks on cancer cells by macrophages, natural killer (NK) cells, and tumor-infiltrating lymphocytes.
  7. Interferons
    • *Slow tumor cell division
    • *Stimulate the growth and activation of NK cells
    • *Help cancer cells¬† resume a more normal appearance and function
    • *Inhibit the expression of oncogenes
  8. Thalidomide (Thalomid)
    Reduce the level of tumor angiogenesis factor (TAF)
Author
tkayrm
ID
166658
Card Set
Common Biological Response Modifiers
Description
Common Biological Response Modifiers used as Supportive Cancer Therapy
Updated