Congenital infection

  1. Varicella
    • Less than 20 weeks pregnancy: congenital varicella (limb hypoplasia, microcephaly, cataracts, growth retardation, skin scarring). High mortality.
    • Second to third trimester: herpes zoster in an otherwise healthy infant.
    • Minus seven days to plus seven days after delivery: severe and even fatal disease (30% mortality).
  2. Congenital CMV infection
    Microcephaly, seizures, neonatal jaundice, hepatosplenomegaly, deafness and mental retardation
  3. Congenital CMV
    Mental retardation, Spasticity, Eye abnormalities, Hearing defects, Enlarged liver
  4. Congenital toxoplasmosis
    Risk of fetopathy is reduced by more than 50% if spiramycin, which can prevent maternal-fetal transmission, is given to mothers.
  5. CMV
    Petechiae and hepatosplenomegaly thrombocytopenia and partially conjugated hyperbilirubinaemia. Chorioretinitis and intracranial calcification.
  6. CMV
    jaundice, hepatosplenomegaly and microcephaly
  7. Toxoplasmosis
     hydrocephalus, seizures and chorioretinitis.
  8. Rubella
    cataracts, cardiac abnormalities, thrombocytopaenia and cerebral calcification.
  9. Rubella
    • Deafness 5-7
    • Cataracts 8-9
    • Cardiac defects 5-10
Card Set
Congenital infection
Congenital infection