-
Mucosa
Inner lining with mucus glands, constantly turning over, new lining every 7 days.
- Pharynx & Rectum= stratified squamous epithelium no absorption here
- Stomach, Small In & Large In = simple columnar epithelium with goblet cells (mucus)absorption of nutrients, vitamins, and water here.
-
Submucosa
Dense irregular connective tissue with blood & lymph vessels, nerves, glands.
-
Muscularis externa
- 2 layers of smooth muscles causes mixing and peristalsis
- circular layer – inner
- longitudinal layer – outer
-
Serosa
visceral peritoneum – tough outer covering, continuous with the mesentery.
-
occlusal surface
the opposing or chewing surface of a tooth.
-
Buccal, Lingual, and Labial sides of Teeth.
- buccal side– near the cheek
- lingual side – near the tongue
- labial side – near lips
-
Types of Teeth
- Incisor – cutting teeth
- Cuspids – canines – conical
- Bicuspids – premolars
- Molars- grinding teeth
-
Where is the swallowing Center
The Medulla
-
Esophagus
is a hollow muscular tube with mucus glands, to the left and posterior of the trachea. Stratified squamous epithelium.
-
Stomach
- Takes food from esophagus and liquefies it into chyme.
- Creates a pH of 2.0 to activatethe enzyme pepsin, which digests protein. Simple Columnar epithelium.
-
GERD
(gastro-esophageal reflux disease)
Lower esophageal sphincter doesn’t closecompletely and allows the return or reflux of stomach contents into the esophagus.
-
Hiatal Hernia
Opening in the diaphragm is too large and allows protrusion of the stomachthrough the diaphragm.
-
Special cells of the Stomach (4)
- 1. Parietal cells = HCl
- 2. Chief cells = pepsinogen
- 3. Goblet cells = are all over stomach surface, create a bicarbonate mucous to protect surface.
- 4. G cells – produce Gastin – hormone – (hormone goes by blood back to the stomach.) Gastin stimulates parietal cells to release more HCl, and stimulates gastric motility.
-
Enteroendocrine Cells-ECL
Enteroendocrine cells, ECL, are like Mast cells since they release histamine which also activatesthe parietal cells and cause the release of HCl.
-
What is absorbed in the stomach?
Water and Alcohol ONLY!
-
Small Intestine
Majority of digestion and absorption of all nutrients occurs here.Simple columnar epithelium absorbs all the products of digestion in the small intestine.
-
Plicae
circular folds of mucosa or plicae that increase the absorptive surface area.
-
Microvilli contain these enzymes to aid in digestion
Brush Border Enzymes
-
Duodenum
- First short section after the stomach, only 1 ft long
- Pancreatic enzymes and gall bladder bile enter the duodenum.
-
Duodenum also releases several hormones to coordinate digestion.
- 1. Secretin – from duodenum, increases gall bladder’s release of bile
- increases pancreas’s release of bicarbonate
- decreases stomach’s motility
- 2. Cholecystokinin –CCK -from duodenum, increases gallbladder’s release bile
- increases pancreas’ release enzymes
-
Pancreas
- inferior and posterior to the stomach.
- 1. Bicarbonate ion, HCO-3 to neutralize stomach acid and activate pancreatic enzymes
- 2. Exocrine function- enzymes- Amylase, Trypsin, Chymotrypsin, LipasePancreas is responsible for digestion of all food items and has enzymes to breakdown each type offood, carbohydrates, proteins and fats.
- 3. Endocrine function- hormones –Isles of Langerhans - insulin and glucogon
-
Large Intestine
- Cecum, appendix
- Ascending Colon
- Transverse Colon
- Descending Colon
- Sigmoid Colon
- Rectum
- Anus
-
The Large Intestine does what?
- 1. Reabsorbs water from chyme
- 2. Absorb vitamins from resident bacteria, vitamin K,
- 3. Store waste temporarily, external sphincter, voluntary control
-
Neural Mechanisms controlling digestion-
- 1. Cephalic phase- think, smell, taste food, the phase before it reaches the stomach
- 2. Gastric phase- Gastric release by stimulation
- 3. Intestinal phase-
-
Hormonal Control – hormones that are released in the presence of chyme or food
- Gastrin – from stomach G cells, increases enzymes release and motility of stomach
- Secretin – from duodenum, increases gall bladder’s release of bileincreases pancreas’s release of sodium bicarbonatedecreases stomach’s motility
- Cholecystokinin – from duodenum, increases pancreas’ release enzymes and increases gallbladder’s release biledecreases stomach’s motility
-
Liver
inferior to the diaphragm, produces bile that is stored in the gall bladder.
-
Gall Bladder
stores bile made by liver. The cystic duct drains the gall bladder into the Common bile duct.
-
Liver’s Functions (7)
- 1. Detoxifies blood
- 2. Removes large proteins from the blood, plasma proteins, Red Blood Cells, big things.
- 3. Carbohydrate metabolism – stores excess glucose as glycogen
- 4. Lipid metabolism- makes materials cells need, phospholipids for cell membranes and makesthe HDL and LDL fats that circulate to the cells and eventually become fat storage.
- 5. Protein metabolism
- 6. Synthesis of Bile
- 7. Storage of Nutrients
-
The liver makes important plasma proteins – such as:
- Albumin – acts as a protein buffer and maintains osmotic pressure in plasma
- Clotting factors –are required to stop bleeding and form a fibrin mesh or clot.
- Complement – work with macrophages (Non Specific) and antibodies (Specific) Defense Systems
|
|