-
-
Monoclonal spike on serum electrophoresis (M-protein):
Multiple myeloma
-
Smudge cells on peripheral smear:
CLL
-
�Palpable olive�:
Pyloric Stenosis
-
�String sign� (long narrow pyloric lumen):
Pyloric Stenosis
-
�Bag of worms� in scrotum:
Varicocele
-
�Boggy uterus�:
Adenomyosis
-
Steeple sx on x-ray:
croup
-
Thumb sx on x-ray:
epiglottitis
-
�Cherry red spot� (red fovea) on Fundoscopy:
CRAO
-
�Blood and Thunder retina�:
CR Vein occlusion
-
Rust-colored sputum:
Strep. Pneumo PNA
-
Currant Jelly sputum:
Klebsiella pneumo. PNA
-
Unilateral ptosis, anhidrosis, miosis:
Horner�s Syndrome
-
Parenchymal bullae or subpleural blebs:
Emphysema (patho.)
-
ECG: S1Q3 inverted T3:
cor pulmonale from PE
-
CXR honeycombing:
pulmonary fibrosis or bronchiectasis
-
Lung bx: nonencaseating granulomas:
Sarcoidosis
-
�Hot potato voice�:
peritonsillar abscess
-
CXR visceral pleural line or �deep sulcus sign� on supine:
PTX
-
Pharyngeal gray pseudomembrane:
Diphtheria
-
Electrical alternans on ECG:
cardiac effusion (patho.)
-
Osler nodes (pnful finger, toe, feet lesions), Janeway lesions (pnless palm and sole lesions), Roth spots (exudative retinal lesions/hemhorrages):
Infective Endocarditis
-
Bite cells (loss of Heinz body) on peripheral smear:
G6PD deficiency
-
Heinz bodies on peripheral smear:
G6PD def. or thalassemia
-
�Beefy red tongue�:
pronounced anemia
-
-
Macro-ovalocytes and hypersegmented PMNs:
Folate def. anemia (patho.)
-
Pancytopenia with circulating blasts:
acute leukemia
-
Auer rods on peripheral smear (needle-like inclusions in eosinophiles):
AML (can also be ALL, but less likely)
-
-
Reed-Sternberg Cells on LN bx:
Hodgkin�s Lymphoma
-
Rouleau Formation on peripheral smear:
Multiple Myeloma
-
Bence Jones Proteins in urine:
Muliple Myeloma
-
�Parrot-beaked� esophagus (dilated esophagus taper to the distal obstruction) on barium swallow:
Achalasia
-
Cobblestone-pattern filling defects with segmental areas of involvement (skip lesions) on Barium enema or CT:
Chron�s Dz.
-
Currant Jelly stools:
Intussusception
-
Sausage-like mass on abdominal exam:
Intussusception
-
Chvostek�s Sign (twitch facial nerve on tap):
Hypocalcemia
-
Trousseau�s Sign (carpal tunnel spasm with BP cuff for 3 min.):
Hypocalcemia
-
Herberden�s nodes (DIP nodes):
OA
-
Bouchard�s nodes (PIP nodes):
OA
-
Swan neck deformity (flexed DIP, extended PIP, flexed MCP):
RA
-
Boutinniere deformity (extended DIP, flexed PIP):
RA
-
Subcutaneous nodules on extensor surfaces:
RA (patho.)
-
Koebner�s phenomenon (maculopapular rash elicited by scratching that appears in the evening):
Juvenile RA
-
�Cup and Saucer� appearance of proximal phalanx on x-ray:
Psoriatic arthritis
-
Tinel�s sign (percussion of volar wrist causes tingling):
Carpal Tunnel
-
Phalen�s sign (wrist flexion for 1 min causes pain):
Carpal Tunnel
-
Fx of 5th MC neck:
Boxer�s fx
-
Distal radial fx with dorsal angulation:
Colle�s fx
-
Distal radial fx with volar angulation:
Smith�s fx
-
Sprain of ulnar collateral ligament of thumb:
Gamekeeper�s thumb
-
Anterior fat pad sign:
hemarthrosis in radial head fx
-
Anatomical snuffbox pain:
Scaphoid fx
-
�Bamboo appearance� on x-ray of spine:
Ankylosing Spondylitis
-
�Cresent sign� of hip on x-ray:
Avascular necrosis of hip
-
Posterior Fat pad sign:
Radial Head fx
-
Amyloid plaques and neurofibrillary tangles:
Alzheimer�s
-
Battle sx:
Basilar skull fx
-
WBC casts:
pyelo. (or nephritis)
-
Hyaline casts:
ARF (or normal in athletes)
-
Renal Tubular Epitheleal cell casts (�muddy brown casts�):
ATN
-
RBC casts:
glomerulonephritis
-
Positive Finkelstein (pain with fist ulnar deviation):
DeQuervain�s
-
Pedunculated bone mass capped in cartilage:
Osteochondroma
-
Gottron�s sx (scaly, papule rash on dorsal hands):
Dermatomyositis
-
Heliotrope rash (eyelid erythema):
Dermatomyositis (or SLE)
-
Low morning cortisol with elevated ACTH:
Addison�s disease
-
More than 125 mg/dL urine cortisol in 24 hours:
Cushings
-
Milkman lines or Looser zones (pseudofractures):
Osteomalacia
-
Eruptive and tendious xanthomas:
Hyperlipidemia (patho.)
-
Petechial rash with meningeal sxs:
Neisseria Meningitidis
-
KOH hyphae and spores (�spaghetti and meatballs�):
Tinea versicolor
-
S-shaped burrows on skin:
Scabies
-
�Snowstorm� on TVU with elevated BHcg:
Hydatidiform mole
-
�Rope-like� on CBE:
Fibrocystic breasts
-
Herald patch then �Christamas tree� appearing rash:
Pityrasis Rosea
-
Oncholysis with oil spots:
Psoriasis (patho.)
-
Hot tub folliculitis:
Pseudomonas aureginosa
-
Terry�s nails (white nail bed):
Liver disease/cirrhosis
-
Azure (blue) lunulae on nails:
Wilson�s disease
-
Absent or decreased femoral pulses with a murmur:
Coarctation of the aorta (patho.)
-
Kayser-Fleischer rings (brown rings btw iris and cornea):
Wilson�s Disease
-
Boot-shaped heart:
RVH from Tet. Of Fallot
-
�Egg on a string� (narrow mediastinum):
Transposition of Great Vessels
-
Lower BP in arms vs legs:
Coarct. Aorta
-
Barking cough like a seal:
Croup
-
�Figure 3 sign� on CXR:
Coarct. Aorta
-
�Machine-like� murmur:
Patent Ductus Arteriosis
-
Absence of �Scottie-Dog� sign on spinal film:
Spondyloysis
-
Inability to pass NGT in an infant:
Choanal Atresia
-
Palpable, non-tender gallbladder (Courvoisier�s sign):
Pancreatic CA
-
Charcot�s triad (fever, chills, RUQ pain, jaundice):
Ascending Cholangitis
-
�Bird beak� deformity on x-ray:
Achalasia or Sigmoid Volvulus
-
Apple-core lesion on Barium Enema:
Colon CA
-
Lead pipe deformity (loss of normal haustral markings) on Barium Enema:
UC
-
Clue cells on wet-prep and positive Whiff test (amine odor):
BV (Gardnerella vaginalis)
-
�Strawberry� Cervix:
Trichomonas
-
Hyphae and buds on KOH Prep:
Vaginal Candidiasis
-
�String sign�/ Sign of Kantor (Stricture or Stenosis) on Barium Enema:
Chron�s disease
-
Chandelier Sign on pelvic/speculum exam (cervical motion tenderness):
PID
-
Koplik spots-grains of sand on an erythematous base (Blue-White buccal lesions):
Measles/Rubeola (patho.)
-
�Sandpaper� rash (like sunburn with goosebumps):
Scarlet Fever
-
�Strawberry tongue�:
Scarlet Fever
-
�Honey� golden crusts on face:
Impetigo (Streptococcus Pyoderma)
-
Gram-positive, encapsulated, box-shaped rods in chains:
Cutaneous Anthrax
-
�Rice-water� diarrhea (gray, turbid, and without odor, blood, or pus):
Cholera
-
�Pea-soup� Diarrhea:
Enteric/Typhoid fever
-
Hyperplastic prickle cells with excess keratin:
HPV skin warts
-
Koilocytotic squamous cells or vacuolated Squamous epithelial cells in clumps on Pap:
HPV cervical warts
-
Multinucleated giant cells on Tzanck Smear:
Herpes Simplex Virus
-
Intracytoplasmic inclusions (�owl�s eyes�) on tissue biopsy:
CMV
-
�Pizza pie� (neovascularization with profliferation) on Fund:
CMV
-
�Satellite lesions� on buttocks:
Diaper dermatitis with candida
-
�Bull�s eye� skin lesion:
Erythema Migrans from Lyme Dz.
-
�String of Pearls� on ovarian US:
PCOS
-
�Sack of grapes� or �grape-like vesicles� on TVU:
Complete Hydatidiform Mole
-
5 Ps (purple, planar, polygonal, pruritic papule):
Lichen Planus
-
Lesions that have white lines (Wickham�s striae):
Lichen Planus
-
�Slapped cheek� syndrome:
Parvovirus B19/ Fifth�s Dz/ Erythema Infecticosum
-
Cobblestoning on colonoscopy:
Crohn�s Disease
-
Dance sign (no BS in RLQ):
Intussesception
-
Rovsing sx (LLQ palpation produces RLQ pain):
Appendicitis
-
Aaron sx (McBurney�s point palpation causes stomach or chest pain):
Appendicitis
-
Gram (-) intracellular diplococci:
Neisseria gonorrheae
-
Chadwick sign (blue cervix):
Pregnancy
-
Hairlike cytoplasmic projections on lymphocytes:
Hairy Cell Leukemia
-
�Tea and Toast diet�:
Folate Deficiency
-
Perihilar infiltrates (�butterfly pattern�):
PCP PNA
-
�Floppy baby syndrome�:
Botulism
-
Rose spots after initial infection symptoms:
Typhoid fever (and other Salmonella infections)
-
(+) Widal agglutination test:
Typhoid fever
-
�Whirlpool� of intraluminal worms on KUB:
Ascariasis (Ascaris Lumbricoides)
-
Pear-shaped trophozoites with 2 nuclei and 4 flagella:
Giardia
-
Multiple ring-enhancing lesions on brain CT or MRI in HIV pt:
Toxoplasmosis
-
(+) Heterophil antibodies (monospot):
Mononucleosis
-
Negri bodies on brain tissue:
Rabies
-
Vesicular rash at different stages:
Varicella
-
Nikolsky�s Sign (manual pressure separates epidermis from the dermis):
Pemphigus Vulgaris (or toxic epidermal necrolysis)
-
Coral red fluorescence with Wood�s lamp:
Erythrasma
-
Bile stained eggs and proglottids in stool exam:
Fish tapeworm
-
Flagellated, curved, oxidase (+) gram (-) rods in stool:
Campylobacter jejuni
-
�Coin-shaped� or �Discoid� plaques with vesicles and papules:
Nummular eczema
-
Encapsulated organisms on India Ink:
Cryptococcus neoformans
-
�Fungus ball� on CXR:
Aspergillus fumigatus PNA
-
Umilicated papules:
Molluscum Contagiosum
-
-
�Pill-rolling� tremor:
Parkinsons
-
�Moon facies and buffalo hump�:
Cushings
-
Spontaneous Hemarthroses:
Hemophilia
-
Triple Layered sputum:
Brochiectasis
-
Cafe aulait spots and rubbery skin nodules:
Neurofibromatosis
-
�Stuck on� waxy lesion:
Seb. K
-
(+) Scotch tape test:
Pinworms
-
Anatomical Snuffbox tenderness:
Scaphoid fx
-
Spontaneous Hemarthroses:
Hemophilia
-
Distended neck veins, decreased BP, muffled heart sounds- Beck's Triad:
Cardiac tamponade
-
Double bubble sign on abd xray:
Duodenal atresia in an infant
-
Auspitz sign (pin point bleed on peeling of scab):
Psoriasis
-
�Onion skin" appearance on x-ray :
Ewings sarcoma
-
Rodent ulcer:
Basal cell ca
-
Prominent epicanthal folds, sandal toe, and simian creases:
Downs Syndrome
-
Heavy, painless vaginal bleeding in the 2nd or 3rd trimester:
Placentia previa
-
Heavy, painful vaginal bleeding in the 2nd or 3rd trimester:
Placenta abruption
-
Presence of a paratesticular nodule at the superior aspect of the testicle, with its characteristic blue-dot appearance (Blue-dot sign):
testicular appendix torsion (patho.)
-
Delta waves on EKG:
Wolff-Parkinson-White Syndrome
-
Kerley B lines on CXR:
CHF (or pulm. Fibrosis or carcinomatosis)
-
�Ring of fire� on US:
Ectopic Pregnancy
-
Dinner fork deformity:
Colle�s fx
-
Tearing chest pain radiating to the back in a very tall male with long, slender hands/fingers:
Marfan Syndrome � aortic dissection
-
�Dew drops on a rose petal�:
Chicken pox
-
Drusen spots (hard yellow-white deposits in the macula under pigment epithelium):
Macular Degeneration (nonexudative)
-
Brushfield spots (on the iris):
Down�s Syndrome
-
Fund: Arteriolar constriction, flame hemorrhages, cotton wool spots, hard exudates:
HTN Retinopathy
-
Fund: Cotton wool spots, hemorrhages, microaneurysms, hard exudates, venous dilatation:
Nonproliferative DM Retinopathy (early)
-
Fund: Cotton wool spots, hemorrhages, microaneurysms, hard exudates, neovascularization:
Proliferatvie DM Retinopathy (late)
-
Negative Birefringent needle-shaped crystals (parallel and yellow):
Gout
-
Positive Birefringent rhomboid-shaped crystals (Perpendicular and blue):
Pseudogout
-
�Sunburst� on bone x-ray:
Osteosarcoma
-
Bubbly lytic lesion on x-ray (�ground-glass�):
Fibrous Dysplasia
-
�Corkscrew� esophagus on barium swallow:
Esophageal spasm
-
Cullen and Grey-Turner sxs:
Necrotizing Pancreatitis (also in ectopic)
-
-
�Shaggy� mucosa on barium swallow:
Candida
-
Multiple, small, volcanic-shaped ulcers on barium swallow:
Herpes
-
Large, deep linear ulcers on barium swallow:
CMV
-
Hazy/steamy cornea with a fixed, dilated pupil:
Angle-closure glaucoma
-
Bell-clapper deformity:
Abnormal attachment of testis in the scrotum (risk factor for torsion)
-
Prehn sign (pain relieved with elevation of scrotum):
Epididymitis
-
�Racoon eyes�:
Orbital fx
-
CSF oligoclonal bands:
MS
-
Lhermitte sign (electrical feeling down the back with neck flexion):
MS
-
Hemorrhagic necrosis of temporal lobes on CT:
Herpetic encephalitis
-
Intravenous inclusions/Pick bodies:
Pick dz.
-
Pellagra (diarrhea, dermatitis, dementia):
Niacin def.
-
Diffuse vacuolar changes of gray matter with reactive astrocytosis on cortical bx: Creutzfeldt-Jakob Dz.
-
�Eggshell� pattern from calcified LNs on CXR:
Silicosis
-
Low plasma rennin with increased 24 hour urine aldosterone:
Hyperaldosteronism
-
Dimple sx on ant. Medial surface of the knee:
Posterolateral knee dislocation
-
Yellow CSF from hemolysis (xanthochromia):
Subarachnoid bleed
-
Hanging teardrop sign (herniation of orbital fat into max. sinus):
Orbital fx
-
Open bomb-bay door sign (bone fragments in the sinus):
Orbital fx
-
Silver, copper-wiring and AV nicking on Fund.:
HTN retinopathy
-
Westmark sign (regional area of decreased pulm. Vascularity on CXR:
PE
-
Peripheral wedge-shaped consolidation/shadow on pleural surface (Hamptom hump):
PE
-
Shoulder sx (bulge of pyloric m. into the antrum):
Pyloric Stenosis
-
Kayser-Fleisher rings (green-yellow ring around cornea):
Wilsons dz
-
Synovial proliferation with pannus formation:
RA
-
Codman�s sign (peri-osteal elevation that forms an angle with the bone cortex):
Osteosarcoma
-
Bilious vomiting and abdominal distention in a newborn:
Duodenal atresia
-
A single or hypoechoic ring with a hyperechoic center (target/donut sign) on US: Intussusception
- �Thumbprinting� of bowel:
- Ischemia
-
�Sentinel Loop� or �Colon cut-off sx� of gas pattern on KUB:
Pancreatitis
-
Curschmann spirals (mucus casts in small airways):
Asthma
-
Signet Ring (thick bronchial walls) on CXR:
Bronchiectasis
-
Schaumann�s bodies and asteroid bodies:
Sarcoidosis
-
Virchow�s node (L supraclavicular LAD):
Mets from GI tumor
-
Anti-glomerular Basement membrane Abs with hematuria and hemoptysis:
Good-Pasteur�s Syndrome (patho.)
-
Honey-combing with calcified parietal pleural plaques:
Asbestosis
-
-
Pericardial Friction rub:
Pericarditis
-
�Water bottle� appearance of cardiac silhouette:
Pericardial effusion
-
Erythema Marginatum (�bathing suit distribution�):
Rheumatic fever
-
Murmur with wide pulse pressure:
Aortic Insuff.
-
Osborn wave aka. J wave (upward deflection of S wave):
Hypothermia (patho.)
-
�Diamond-shaped murmur� (crescendo-decrescendo) on precordial chest:
Aortic Stenosis
-
Mid-systolic click:
Mitral Valve Prolapse
-
Opening snap murmur:
Mitral stenosis
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