pharma endocrine

what are the forms of insulin that are available iv?

llispro and regular
which insulin has no peak?

glargine insulin - so there is no chance of hypoglycemia
what is the MOA of insulin?

binds to transmembrane receptor activating tyrosine kinase to phosphorylate tissue specific substrate
name ketoacids ?

acetate(fruity smell) , acetoacetate . beta hydroxybutyrate
what is the MOA of sulfonylureas ?
name the drugs that block and open ATP dependent potassium channels ?
- open - minoxidil and diazepoxide - cause hyperglycemia
- close - sulfonylureas - causes hypoglycemia
why are metformins called as glucophage?

because it causes the tissues to eat up glucose , because it causes increased sensitivity to insulin
what is the MOA of metformin?

it increases tissue sensitivity to insulin and decreases hepatic gluconeogenesis
which hypoglycemic causes euglycemia?

metformin - reduces postprandial hyperglycemia but doesnot cause hypoglycemia
name alpha glycosidases inhibitors ?

acarbose and miglitol
name thiazolidinediones?

pio and rosi glitazones
what is incretin ?

they are released from small intestine and increase the secretion of insulin by acting on beta cells. it is also called as GLP
name GLP?

exenatide
name the drugs acting on GLP?

Author

Anonymous

165407

Card Set

pharma endocrine

Description

hypoglycemic drugs

Updated

2012-08-09T15:20:15Z

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