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What are the three types of granulocytes
- 1. Neutrophils
- 2. Eosinophils
- 3. Basophils
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What are the mononuclear phagocytes
- 1. Monocytes
- 2. Macrophages
- 3. Dendritic cells
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What is the last type Luekocyte which has several types
Lymphocytes
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What are other names for neutrophils
polymorphnuclear neutrophillic leukocyte, PMNs, or polys
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What percentage of leukocyte do neutrophils make up?
55-65%
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Location of neutrophils in the body
account for most of the circulating leukocytes; few in tissues except during inflammation
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percentage of Eosinophils
2-4%
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percentage of Basophils,
0-1%
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Another form of basophils
mast cells
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location of Eosinophils in the body
few in tissues except in certain types of inflammation and allergies
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function of neutrophils
phagocytize and digest engulfed materials
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function of Eosinophils
participate in inflammatory reaction and immunity to some parasites
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location of basophils in the body
Basophils in circulation; mast cells present in most tissues
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Function of basophils
release histamine and other inflammation inducing chemicals from the granules
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percentage of monocytes
3-8%
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location of monocytes in the body
in circulation; they differentiate into either macrophages or dendritic cells when they migrate into tissue
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function of monocytes
phagocytize and digest englufed materials
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Location of macrophages in the body
present in vitually all tissues; given various names based on the tissue in which they are found.
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function of the macrophage
phagocytize and digest engulfed materials
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location of dendritic cells
initally in tissues, but they migrate to secondary lymphoid organs (such as lymph nodes, spleen, thymus, appendix, tonsils
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function of dendritic cells
gather antigen from the tissues and then bring it to lymphocytes that congregate in the secondary lymphoid organs
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percentage of lymphocytes?
25-35%
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location of lymphocytes in the body
in lymphoid orgnace (such as lymph nodes, spleen thymus, appendix, tonsils); also in circulation
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Function of lymphocyte
participate in adaptive immune responses
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these turn red and are acidic in nature
Eosionphils
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important in asthma and atopy (prone to hay fever and asthma)
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responsible for arthrus reaction
basophil
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multilobulor and release chemotatic factors
neurophils
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these are also antigen presenting cells (APC). They sense fluids in body and find foreign material and expose the antigen and cause attacks
Dendrites
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these cells are very few in number but very efficient in iling
natural killer cells
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What are the two main types of lymphocytes
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this type of lymphocyte is responsible for humoral immunity. When activated by an antigen it becomes a plasma cell which makes antibodies
B-cells
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this type of lymphocyte is responsible for cellular immunity. Gains Thymetic marker in the thymus
t-cell
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Which type of lymphocyte does HIV attack
b-helper cells
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these degranulate during anaphylaxis
mast cells
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this is the first kindof cell that can become any kind of cell
Pluripotent cell
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carry oxygen
Red Blood Cells (Erythrocytes)
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not true cells. Flakes off megakaryotes. Important for clotting
Platelets
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what is the undifferentiated form of granulocyte
Myeloblast
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which cells can undergo diapedisis (sneak between tissues and get out of blood system and into tissues)
Monocytes
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How is most CO2 carried
in H2CO2 and HCO3
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What law is O2 saturation dependent on
Bohr effect (pH and temperature dependent)
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