Serum Enzymes and Cardiac Markers

26-174 units/L

Reflects tissue catabolism resulting from cell trauma

• CK level begins to rise within 6 hrs of muscle damage
• Peaks at 18 hrs
• Returns to normal in 2-3 days.

detects myocardial or skeletal muscle damage or CNS damage.

• *CK-MB cardiac muscle: 0%-5% of total
•   CK-BB brain tissue: 95%-100% of total
•   CK-MM skeletal muscle: 0%

140-280 units/L

• *begins to rise about 24 hrs after Myocardial Infaction
• *peaks in 48-72 hrs
• *returns to normal within 7-14 days

Testing should be repeated on 3 consecutive days

• Troponin I: <0.6 ng/mL
•                  *>1.5 ng/mL indicates MI
•                  * may remain elevated for 7-10 days

• Troponin T: >0.1-0.2 ng/mL indicates MI
•                   * may remain elevated for as long as 10-14 days

regulatory protein found in striated muscle (skeletal and myocardial)

*Levels elevate as early as 3 hrs after MI

• <90 mcg/L
• * elevation could indicate MI

• ANP: 22-27 pg/mL
• BNP: < 11pg/mL *primary marker for identifying CHF as the cause of dyspnea
• CNP: not yet determined

used to identify clients with CHF