Parkinson's

Parkinson's disease involves degeneration of the
______ ________.

Substantia Nigra
Which drug is the most effective in treatment of PD?

Levodopa
Carbidopa/levodopa

Sinemet - Carbidopa is a decarboxylase inhibitor that prevents peripheral conversion of levodopa to dopamine.
What are all the direct dopamine stimulators?
- Bromocriptine
- Ropinirole
- Apomorphine (must give with trimethobenzamide -antiemetic- concurrently)
- Pramipexole
Which MAO-I are used in treatment of PD?
- Selegiline - comes in ODT form
- Rasagiline
What are the COMT-I used in treatment of PD?
- Entacapone
- Tolcapone
Amantadine

Symmetrel - influenza drug shown to improve PD
Benztropine

Cogentin
Trihexyphenidyl

Artane
Carbidopa-entacapone-levodopa

Stalevo

Author

evelngo

164556

Card Set

Parkinson's

Description

Updated

2012-07-31T15:23:40Z

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