Parkinson's

  1. Parkinson's disease involves degeneration of the
    ______    ________.
    Substantia Nigra
  2. Which drug is the most effective in treatment of PD?
    Levodopa
  3. Carbidopa/levodopa
    Sinemet - Carbidopa is a decarboxylase inhibitor that prevents peripheral conversion of levodopa to dopamine.
  4. What are all the direct dopamine stimulators?
    • Bromocriptine
    • Ropinirole
    • Apomorphine (must give with trimethobenzamide -antiemetic- concurrently)
    • Pramipexole
  5. Which MAO-I are used in treatment of PD?
    • Selegiline - comes in ODT form
    • Rasagiline
  6. What are the COMT-I used in treatment of PD?
    • Entacapone
    • Tolcapone
  7. Amantadine
    Symmetrel - influenza drug shown to improve PD
  8. Benztropine
    Cogentin
  9. Trihexyphenidyl
    Artane
  10. Carbidopa-entacapone-levodopa
    Stalevo
Author
evelngo
ID
164556
Card Set
Parkinson's
Description
PD
Updated