Women's Health

  1. T/F: Women with an intact uterus going through menopause must be treated with both estrogen and progestin.
    TRUE. Women who have had a hysterectomy are treated with unopposed estrogen only.
  2. What are the estrogen-progestin producst available?
    • Femhrt
    • Activella
    • Prempro
    • Premphase
  3. What is the role of Estrogen in Contraceptives? What is the roleĀ  Progestin?
    • Estrogen: prevents development of dominant follicle by suppressing FSH.
    • Progesetin: blocks ovulation. Causes production of thick cervical mucus and atrophy of endometrium.
  4. What are extended cycle OCs?
    They delay menstruation. Occurs around every 3 months or not at all.

    • Loestrin-24 FE
    • Seasonale
    • Jolessa
    • Yaz
  5. Which OC is a continuous-cycle OC?
  6. Which contraceptive is in a transdermal system?
    Ortho Evra
  7. Which contraceptive is a subdermal rod? An injection? An IUD?
    • Implanon
    • Depo-Provera (medroxyprogesterone)
    • Mirena (x 5 years)
  8. SE such as breast tenderness, fullness, nausea, blaoting, HTN, skin discoloration (melasma), HA are usually associated with ______ excess.
  9. SE such as acne, depression, irritability, hypomenorrhea, increased appetite and weight agin, fatigue, constipation is usually associated with ____________ excess.
  10. Early breakthrough bleeding is associated with _________ deficiency, while late breakthrough bleedining is associated with _________ deficiency.
    estrogen; progestin
  11. What is Type I and Type II osteoporosis?
    • Type I: Postmenopausal (most common)
    • Type II: Age related
  12. After completing a DEXA scan, a T score of -1.0 to -2.5 standard deviations below young adult mean is considered to be __________.
  13. After completing a DEXA scan, a T score below -2.5 standard deviations below young adult mean is considered to be __________.
  14. Calcium Citrate (24% calcium content)
  15. Calcium Carbonate (40% calcium content)
    • Caltrate
    • Titralac
    • Tums
    • Viactiv chews
    • Mylanta Supreme liquid
  16. Calcium phosphate tribasic (39% calcium content)
    Posture, Posture-D
  17. What is the MOA of bisphosphonates?
    Bind to bone (hydroxyapatite) and incorporate into bone to increase and stablize bone mass. They also inhibit osteoclasts have have very long half-life in the bone.
  18. Alendronate - brand/dosing?

    Prevention: 5 mg/day or 35mg/wk

    Treatment = x 2 of prevention
  19. Risedronate - brand/dosing?

    • Prevention: 5 mg/day
    • Treatment: 5 mg/day
    • OR 35 mg/wk
    • OR75 mg/day x 2 days/month
    • OR 150 mg/month
  20. Ibandronate - brand/dosing?

    2.5 mg/day, 150 mg/month, 3 mg IV Q3 months
  21. Zoledronic Acid - brand/dosing?

    5 mg IV infusion over 15 minutes QYEAR
  22. Calcitonin
    Miacalcin - INTRANASAL - qd alternating nostrils or SQ or IM QOD

    *Calcitonin inhibits bone resorption by binding to osteoclast receptors.
  23. Teriperatide (PTH hormone)

    Injection daily - increases rate of bone formation by stimulating osteoblasts.
  24. Raloxifene

    60 mg daily
Card Set
Women's Health
Menopause, Contraceptives, Osteoporosis