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When and how often should you take thyroid hormones?
ONCE daily 30 minutes before breakfast
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Do NOT take antacids, calcium, or iron supplements with ____ hours of levothyroxine.
4 hours
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Levothyroxine (T4)
Synthroid, Levothroid
-
Dessicated thyroid
Armour Thyroid
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Liothyronine (T3) - 2
Cytomel, Triostat
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Liotrix (T4 and T3 in a 4:1 ratio)
Thyrolar
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Name the anti-thyroid meds.
- Lugol's solution (strong iodine soln)
- SSKI (saturated solution of potassium iodine)
- PTU (Propylthiouracil)
- Tapazole (Methimazole)
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Which drug is preferred when rapid reduction in thyroid hormone secretion is desired (like in thyroid storm)?
Iodides - they block hormone release and inbit thyroid hormone synthesis.
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Cushing's syndrome is a result from chronic ________ excess.
Glucocorticoid
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Which drugs are used to treat Cushing's Syndrome?
- Ketoconazole (Nizoral) - inhibits enzymes required in cortisol synthesis
- Aminoglutethimide ( Cytadren) - inhibts conversion of cholesterol to pregnenolone (involved in generation of glucocorticoids)
- Mitotane (Lysodren) - cytotoxic drug that suppresses ACTH
- Metyrapone (Metopirone) - decreases cortisol synthesis
-
What is Addison's disease?
Adrenocortical deficiency resulting in glucocorticoid and mineralcorticoid deficiency.
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What lifelong medications are needed in the treatment of Addison's disease?
glucocorticoids and mineralcorticoids (DUH!)
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Cortisone
anti- inflam: mild
Na-retaining potency: mild
t 1/2: short
Cortef
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Hydrocortisone (3)
Cortef, Hydrocortone, Solu-Cortef
- anti- inflam: mild
- Na-retaining potency: mild
- t 1/2: short
-
Prednisone (2)
anti- inflam: medium
Na-retaining potency: mild
t 1/2: medium
Deltasone, Liquid Pred
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Prednisolone (3)
anti- inflam: medium
Na-retaining potency: mild
t 1/2: medium
- Prelone
- Pediapred
- Delta-Cortef
-
Methylprednisolone (2)
anti- inflam: medium
Na-retaining potency: none
t 1/2: medium
Medrol, Solu-Medrol
-
Triamcinolone (3)
anti- inflam: medium
Na-retaining potency: none
t 1/2: medium
- Aristocort
- Kenacort
- Kenalog
-
Dexamethasone (4)
anti- inflam: High
Na-retaining potency: none
t 1/2: Long
- Decadron
- Dexameth
- Dexone
- Hexadrol
-
Betamethasone
anti- inflam: High
Na-retaining potency: none
t 1/2: long
Celestone
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Fludrocortisone
anti- inflam: medium/high
Na-retaining potency: VERY HIGH
t 1/2: medium
Florinef
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What is Cosyntropin and ACTH used for?
Diagnosis of adrenal insufficiency. Cosyntropin is a synthetic peptide that is simular to human ACTH but is less allergenic.
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What are all the dosage forms of testosterone?
Patch, Gel, Injection in oil, Pellet for SQ implantation, Buccal tablet, tablets, capsules
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