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What are some functions of PO4?
- Essential to fxn of muscle, RBCs & nervous system
- Deposited w/Ca2+ for bone & tooth structure
- Plays a role in acid-base buffering, ATP production, cellular uptake of glucose, metabolism of PRO, CHO, fats
- Inverse relationship w/Ca2+
- Primarily excreted by kidneys
- Required for release of O2 from HGB
- Normal 2.7-4.6
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What are some common pathologies of hyperPO4?
- Acute, chronic renal failure
- Hypoparathyroidism
- Overadministration of IV or PO phosphates
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SnSs of hyperPO4
- Hypocalcemia
- Sx look like hypocalcemia
- Deposition of calcium-phosphate precipitates in skin, soft tissue, cornea, viscera, blood vessels
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What are some nursing intervension for the pt w/hyperPO4?
- Restrict food & fluids w/PO4
- Adequate hydration & correction of hypocalcemia
- Administer PO4 binding Rx (Renagel)
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What are some common pathologies of hypoPO4?
- Alcoholism & withdrawal
- Malnourishment, malabsorption
- Use of phosphate-binding antacids
- Prolonged parenteral nutrition w/inadequate replacement
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SnSs of hypoPO4
- Anorexia, malaise, muscle wasting & weakness
- Tachycardia
- Symptoms of hypercalcemia
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What are some nursing intervensions of the pt w/hypoPO4?
- Ingestion of foods ^ in PO4
- Supplemental PO4
- May require IV Sodium Phosphorous or Potassium phosphorous.
- D/C PO4 binding Rx.
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