Neuropath - Trauma and Toxic

Cerebral Contusion 

Favors the basal forebrain and temporal lobes

Diffuse Axonal Injury

Axon retraction balls seen in diffuse axonal injury

Subfalcine Herniation

Uncal Herniation

Compression of CN III

Pigmentation of the globus pallidus as can be seen in Wilson's Disease

Alzheimer Type II Neuron commonly seen in hyperammonemic states with swollen, irregular nuclei and peripheral displacement of the chromatin

Discoloration of the Basal Ganglia as can be seen in Cardbon Monoxide Poisoning, PKAN, and Manganese Toxicity

Discoloration / hemorrhage of the putamen as seen in Methanol Toxicity. Also affect the retinal cells and cerebral white matter.

Wernike’s Encephalitis due to Thiamine deficiency with hemorrhages in the MB and PAG

Central Pontine Myelinolysis

Subacute Combined Degeneration affecting the dorsal column and corticospinal tracts as seen in B12 deficiency