-
What are the ovarian hormones?
- Estrogens
- Progestagens
- Androgens
-
What does the hormone estrogen do?
- Principle estrogen secreted by ovaries is estradiol-17 alpha
- They promote development of female secondary sex characteristics, uterine growth, thickening of vaginal mucosa, thinning of cervical mucus, and development of breast ductal system.
-
What are the different types of progestagens?
- Pregnenolone
- Progesterone
- 17-hydroxyprogesterone (17-OHP)
-
What is pregnenolone?
Precursor for all ovarian steroid hormones
-
What does progesterone do?
- Produced by corpus lutem
- Important fo implantation of fertilized ovum and maintenance of early pregnancy
-
What does 17-hydroxyprogesterone (17-OHP) do?
has little or no biological activity
-
What does the hormone androgen do?
- The ovarian cells produce small amounts of this hormone
- The different types of androgens are:
- Dehydroepiandrosterone (DHEA)
- Androstenedione
- Testosterone
- Dihydrotestosterone
-
What are some pathological states?
- Amenorrhea (absence of bleeding)
- Dysfunctional uterine bleeding (DUB) (uterine bleeding during anovulatory cycles)
- Polycystic ovary syndrome (PCOS) (characterized by infertility, hirsutism, obesity, menstrual disturbances
- Androgen excess
- Ovarian hyperfunction (ovarian neoplasms)
-
What is the main hormone for the male?
Testosterone
-
What are other male hormones?
- All these are made by the testes in small amounts
- Dihydrotestosterone
- Androstenedione
- 17-hydroxyprogesterone
- Progesteron
- Estradiol
- Pregenolone
-
What are pathological states for the male?
- Hypogonadism (failure of testes to produce testosterone, spermatozoa or both
- Testicular hyperfunction (testicular tumors)
- Erectile dysfunction
-
What is infertility and the factors causing it?
- The involuntary inability to conceive
- Factors:
- Female factors 40%
- Male factors 40%
- Combined male and female factors 10%
- Unexplained factors 10%
|
|
