Blood

most abundant plasma protein; made in the liver; maintains the osmotic pressure of the blood

plasma protein that functions as transport factors; coagulation factors; also made in the liver

plasma protein that functions as antibodies; it is made by the lymphocytes

plasma protein that serve as factors for inflammation and destruction of microorganisms

the largest plasma protein; polymerizes as insoluble cross-linked fibers

diameter of erythrocyte

thickness of erythrocyte(side)

thickness of erythrocyte(center)

mature type of these cell lacks nuclei

carries oxygen binding protein(hemoglobin)

gives erythrocytes large surface-to-volume ratio to help facilitate gas exchange

erythrocyte count(female)

erythrocyte count(male)

condition with decreased numbers of erythrocyte

condition with increased number of erythrocyte

condition in which the erythrocyte has >9um in diameter

condition in which the erythrocyte has <6um in diameter

presence of increased percentage of erythrocytes with great variation in size

plasma composition

protein composition in plasma

normal value for erythrocyte count

components of buffy coat

normal value of platelets

differential leukocyte count for basophil

differential leukocyte count for eosinophil

differential leukocyte count for neutrophil

differential leukocyte count for lymphocyte

differential leukocyte count for monocyte

membrane proteins found in erythrocyte that function as anion transporter and antigenic sites that form the basis for blood typing

forms a  lattice reinforcing the membrane

anchors the lattice to band 3 proteins

permits the membrane and cell flexibility required for passage through capillaries and important for the normal low viscosity of blood

fills the erythrocyte cytoplasm; tetrametric; oxygen-binding protein

oxygen + hemoglobin

carbon diaxode + hemoglobin

percentage of erythrocyte in the blood

lies between the plasma and the erythrocytes

disease characterized by mutation of beta-chain of hemoglobin;GAA changed to GV(valine)A

decreased normal blood concentrations of hemoglobin; caused by blood loss; decreased production of erythrocyte; iron deficiency

loss of ucleus and all organelles of an erythrocyte before the cells are released by bone marrow into the circulation

formation of erythrocyte that is formed because of an increase in surface tension

type of metabolic pathway mature erythrocyte relies on

lifespan of RBC

organs that removes senescent or worn-out erythrocytes

key players in defense against invading microorganism

basophil, eosinophil, neutrophil; has 2 or more lobes; has 2 types of granules

granules tat bind neutral, basic or acidic stains; very small

granules that are specialized lysosomes, stain darkly present at some level in leukocytes

enzyme that is bactericidal and generates hypochlorite

bind and produce holes in cell membranes of microorganism

dissolves bacterial cell wall components

appears to have a single nucleus; has azurophilic granules; contains nonspecific granules

trigger loosening of intercellular junctions in the endothelial cells

process where leukocytes sends extensions into the new intercellular openings, migrate ut of the vunules, head directly for bacterial cells

process of attraction of neutrophils to bacteria that involves chemical mediators

appears to have 2-5 lobes; lives 6-7 hours in the blood and 1-4 days in other tissues; circular when inactive; contains glycogen

has vacuoles(phagosomes); engulf by phagocytosis; pH 5.0

neutrophils that hs >5 segments indicates what disease

drum-stick shaped structure in the neutrophils; indicates sexuality(female)

has a bilobed nucleus; has large rod specific granules; fights parasites; phagocytize antigen-antibody complexes and modulate inflammatory responses; has large refractile pink-orange-red granules

proteins responsible for the red-orange-pink staining of the eosinophils

nucleus is divided into two or more irregular lobes; has obscured and blue-black granules; has eosinophilic chemotactic factors; secretes histamin and heparin

has spherical nuclei; T cell, B cell and NK cell

leukocyte that can return after diapedesis

cell mediated immunity

humoral immunity

programmed to kill cancer cells; directly acts

has large, oval, kidney-shaped nucleus; basophilic cytoplasm; has small azurophilic granules

differentiation of monocyte; eat dying and old cell

promote clotting; repair of minor tears or leaks in the walls of blood vessels; 10 day lifespan

lightly stained part of platelet

darker staining granule in the platelet

helps maintain the platelet's ovoid shape

derived from ER and stores calcium; facilitates rapid exocytosis

facilitates platelet uptake of fibrinogen and serotonin of plasma; facilitates rapid exocytosis

role of platelet that allow platelet aggregation to collagen via collagen binding protein

1st step to stop bleeding

platelet plig release adhesive glycoprotein and ADP to induce platelet aggregation and increase the size of platelet plug

fibrinogen and von willebrand factor promote cascade; fibrin to blood clot thrombus

interaction of actin and myosin in the clot

action of proteolytic enzyme plasmin through local action of plasminogen activators; plasminogen from plasma

possess a variety of membrane-bound granules and a sparse population of mitochondria and glycogen particles; has mitochondira and glycogen particles

granules in the central granulomere that has platelet derived growth factor

granules in the central granulomere that has ATP, ADP, and serotonin

granules in the central granulomere that has lysosomal enzymes

disease condiiton with decreased blood coagulation

clotting factor that has a defect in hemophilia A

clotting factor that has a defect in hemophilia B