What should be done if a dose of Acyclovir is missed?
Take as soon as possible but don't double dose
T/F Acyclovir requires plenty of fluid intake?
True
What category of drug is Albuterol sulfate?
Antiasthmatic
What are three brand names for Albuterol Sulfate?
Proventil
Ventolin
Proair
What forms does Albuterol Sulfate come in?
HFA Inhaler and Solution for inhalation
What is Albuteral Sulfate used for?
Relief of bronchospasm in patients with reversible obstructive airway disease
Prevention of expercise induced bronchospasm
Maintenance to prevent exacerbation of bronchospasms
What is the MOA of Albuteral Sulfate?
Stimulates adenyl cyclase, the enzyme that catlyzes the formation of c-AMP from ATP. This relaxes the bronchial, uterine, and vascular smooth muscle by stimulating beta-2-adrenergic receptors
How is Albuteral Sulfate excreted?
Through the urine
Is Albuteral Sulfate systemically absorbed?
No, very minimally
What drugs may increase the toxicity of Albuteral Sulfate?
Sympathomimetics
Tricyclic Antidepressants
Monoamine Oxidase Inhibitors
What may Albuteral Sulfate cause when used with nonpotassium sparing diuretics?
Worsen hypokalemia
Worsen ECG changes
Albuteral Sulfate has what effect on digoxin levels?
May decrease serum digoxin
What pregnancy category is Albuteral Sulfate?
C
What types of patients should use Albuteral sulfate with caution?
Cardiovascular disorders
Hypertension
Hyperthyroidsim
DM
Nursing or Pregnant
What are some adverse effects of Albuteral Sulfate?
Nausea
vomiting
nervousness
headache
insomnia
tremor
dizziness
hypertension
tachycardia
palpitation
How should the mouthpiece for an albuterol inhaler be cleaned?
Weekly, remove canister, run warm water through it for 30 seconds, air dry thoroughly
What is the brand name for Alendronate Sodium?
Fosamax
What category of agent is Alendronate Sodium?
Osteoporosis agent
What dosage forbs does Alendronate Sodium come in?
Tablets and oral solution
What is Alendronate sodium used to treat?
Osteoporosis in postmenopausal women
Prevention or osteoporosis
Increase bone mass
Paget's disease
How should Alendronate sodium be taken?
With plain water, after waking, do not eat or lie for at least 30 minutes after
What is the MOA of Alendronate sodium?
Inhibits osteoclast activity, encourages new bone formation. Not pharmacologically active
Excretion of Alendronate sodium?
Urine unmetabolized
Drug Interactions with Alendronate sodium
Decrease absorption?
Antacids
Calcium
Drug Interactions with Alendronate sodium
GI adverse effects?
Aspirin
Pregnancy category of Alendronate sodium?
C
Contraindicated patients for Alendronate sodium?
Can't sit upright for 30 minutes
Hypocalcemia
Delayed esophageal empting
Creatine clearance less than 35
Adverse effects of Alendronate Sodium?
Abdominal pain
constipation
diarrhea
flatulence
musculoskeletal pain
Should Alendronate sodium be double dosed?
No, if dose is missed wait until next scheduled time
What category of drug is Allopurinol?
Agent for gout
What is the brand name for Allopurinol?
Zyloprim
What forms is Allopurinol available in?
Tablets
Solution for injection
What is Allopurinol indicated for?
Treatment of gout, uric acid nephropathy
prevention of uric acid nephropathy
Prevention of gouty arthritis flare ups
Secondary hyper uricemia
Treatment of recurrent calcium oxalate stones
How does Allopurinol work?
Competitively inhibits xanthine oxidase so hypoxanthine cannot be converted touric acid
Drug Interactions with Allopurinol?
Allopurinol can cause what type of rash?
ampicillin induced
Drug Interactions with Allopurinol
What drugs does Allopurinol increase the toxic effects of?
Thiopurines (mercaptopurine and azathiopurine)
Chlorpropamide
Pregnancy catergory of Allopurinol?
C
Adverse effects of allopurinol?
Drowsiness
diarrhea
nausea
vomiting
abdominal pain
rash
Caution should be used in what type of patient when using Allopurinol?
Renally impaired
How much urine output should a patient using allopurinol have?
At least 2 liters a day
Does Allopurinol work instantaneously?
No, may take one or more weeks.
What beverage should be avoided while on Allopurinol?
alchol
What should be done if a dose of Allopurinol is missed?
