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What are some of the symptoms associated with anxiety?
- 1) fear
- 2) worry
- 3) tachycardia
- 4) palpitations
- 5) SOB
- 6) GI upset
- 7) pain
- 8) chest pain
- 9) insomnia
- 10) fatigue
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What are some common types of anxiety disorders?
- 1) generalized anxiety disorder (GAD)
- 2) panic disorder (PD)
- 3) social anxiety disorder (SAD)
- 4) obsessive compulsive disorder (OCD)
- 5) post-traumatic stress disorder (PTSD)
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What are some treatments for anxiety disorders?
- 1) lifestyle modifications
- 2) antidepressants
- a. SSRIs
- b. SNRIs
- c. TCAs
- 3) benzodiazepines
- 4) natural products
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What are some lifestyle modifications that you can apply in patients with anxiety disorders?
- 1) increase physical activity
- 2) talk therapy
- 3) helping others
- 4) community involvement
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What are some SSRIs used in the treatment of anxiety disorders?
- 1) citalopram (Celexa)
- 2) escitalopram (Lexapro)
- 3) fluoxetine (Prozac)
- 4) Fluvoxamine (Luvox)
- 5) paroxetine (Paxil)
- 6) sertraline (Zoloft)
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What are some SNRIs used in the treatment of anxiety disorder?
- 1) duloxetine (Cymbalta)
- 2) venlafaxine (Effexor)
-
What TCAs are used in the patients with anxiety disorders?
- 1) doxepin (Silenor)
- 2) imipramine (Tofranil)
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What drugs are used for OCD?
- 1) citalopram (Celexa)
- 2) fluoxetine (Prozac)
- 3) fluvoxamine (Luvox)
- 4) paroxetine (Paxil)
- 5) sertraline (Zoloft)
-
What drugs are used for PD?
- 1) citalopram (Celexa)
- 2) fluoxetine (Prozac)
- 3) paroxetine (Paxil)
- 4) sertraline (Zoloft)
- 5) venlafaxine (Effexor)
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What drugs are used to treat GAD?
- 1) escitalopram (Lexapro)
- 2) paroxetine (Paxil)
- 3) duloxetine (Cymbalta)
- 4) venlafaxine (Effexor)
-
What drugs are used to treat SAD?
- 1) fluvoxamine (Luvox)
- 2) paroxetine (Paxil)
- 3) sertraline (Zoloft)
- 4) venlafaxine (Effexor)
- 5) buproprion (Aplenzin, Budeprion SR, Budeprion XL, Buproban, Wellbutrin SR, Wellbutrin XL, Wellbutrin, Zyban)
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What drugs are used to treat PTSD?
paroxetine (Paxil)
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What drugs can be used for relief of acute symptoms, however, not for treatment of the causes of anxiety?
benzodiazepines
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What is the dose for lorazepam (Ativan)?
0.5 - 2 mg prn
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What is the dose for alprazolam (Xanax)?
0.25 - 2 mg prn
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What is the dose for clonazepan (Klonopin)?
0.125 - mg 2 mg prn
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What is the dose of diazepam (Valium)?
2 - 10 mg prn
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What is the dose for chlordiazepoxide (Librium)?
5 - 25 mg prn
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What is the dose of oxazepam (Serax)?
10 - 30 mg prn
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What are the side effects associated with benzodiazepine use?
- 1) C - IV
- 2) potential abuse
- 3) physiological dependence
- 4) tolerance
- 5) withdrawal symptoms when d/c
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What are some natural products used for anxiety disorders?
- 1) valerian
- 2) lemon balm
- 3) glutamine
- 4) passion flower/hops
- 5) chamomile tea
- 6) theanine
- 7) skullcap
- 8) kava
- a. can cause damage to the liver
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What is the starting dose of buspirone (Buspar)?
7.5 mg BID
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What is the maximum dose of buspirone (Buspar)?
60 mg/day
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What are the side effects associated with buspirone (Buspar)?
- 1) Nausea
- 2) HA
- 3) dizziness
- 4) excitement
- 5) kidney damage
- 6) liver damage
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What class of drugs should you avoid using while taking buspirone (Buspar)?
MAOIs
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When should you consider decreasing the dose of buspirone (Buspar)?
- When taking:
- 1) erythromycin
- 2) diltiazem
- 3) verapamil
- 4) 3A4 inhibitors
- a. cimetidine
- b. amiodarone
- c. aprepitant
- d. atazanavir
- e. caffeine
- f. clarithromycin
- g. clotrimazole
- h. conivaptan
- i. cycloSPORINE
- j. delavirdine
- k. desipramine
- l. diltiazem
- m. doxycycline
- n. efavirenz
- o. erythromycin
- p. fluconazole
- q. fosamprenavir
- r. fosaprepitant
- s. fospropofol
- t. haloperidol
- u. imatinib
- v. indinavir
- w. isoniazid
- x. itraconazole
- y. ketoconazole
- z. lidocaine
- aa. metroNIDAZOLE
- bb. miconazole
- cc. nefazodone
- dd. nelfinavir
- ee. niCARdipine
- ff. norfloxacin
- gg. propofol
- hh. quiNIDine
- ii. ritonavir
- jj. saquinavir
- kk. sertraline (Zoloft)
- ll. sitaxsentan
- mm. telithromycin
- nn. tetracycline
- oo. verapamil
- pp. voriconazole
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When should you consider increasing the dose of buspirone (Buspar)?
- When taking:
- 1) rifampin
- 2) 3A4 inducers
- a. phenobarbital
- b. phenytoin
- c. armodafinil
- d. bosentan
- e. carBAMazepine
- f. dexamethasone
- g. efavirenz
- h. fosphenytoin
- i. nafcillin
- j. nevirapine
- k. OXcarbazepine
- l. PENTobarbital
- m. primidone
- n. rifabutin
- o. rifapentin
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What are some drugs that can worsen anxiety?
- 1) albueterol
- 2) caffeine
- 3) stimulants
- 4) decongestants
- 5) steroids
- 6) buPROPion
- 7) fluoxetine
- 8) illicit drugs
- a. cocaine
- b. LSD
- c. methamphetamine
- 9) aripiprazole (Abilify)
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