What does cyclooxygenase do?
- COX 1 ~ Found in ALL tissue “Housekeeper”
- --Protects gastric mucosa
- --Supports renal function
- --Promotes platelet aggregation
- COX 2 ~ Found in Injured tissue
- --Mediates inflammation
- --Sensitizes receptors to painful stimuliIn brain
- --Mediates fever
- --Contributes to perception of pain