Drug & Polymer Properties

Restenosis Cascade
- Thrombosis
- Inflammation
- Proliferation
- Migration
- Healing
Everolimus targets which stage of the restenosis cascade?

Inflammation (anti-inflammatory agents) & Proliferation (anti-proliferative agents)
Paclitaxel targets which stage of restenosis?

Proliferation (anti-proliferative agents)
Everlimus is the active agent in what drug?

Certican (Novartis) - used for prevention of rejection of heart, kidney & lung transplants
Why Everlimus is the ideal drug
- Proven clinical performance: efficacious and safe
- Preferred Mechanism of Action: cytostatic and non-inflammatory
- Wide therapeutic window: excellent tissue compatibility & effective at multiple doses with minimal toxicity

Author

kellytange

160382

Card Set

Drug & Polymer Properties

Description

The Properties of the ideal drug and polymer

Updated

2012-06-28T15:03:05Z

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