HIV Drugs

  1. HIV Drugs (9)
      1. Zidovudine
      2. Delavirdine
      3. Indidinavir
      4. Didanosine
      5. Efavirenz
      6. Saquinavir
      7. Lamivudine
      8. Tenofovir
      9. Enfuvirtide
  2. Zidovudine
    Mechanism side effects (11) DT (5)
    NRTI

    • Fatigue
    • GI intolerance
    • Nausea
    • Headache
    • Malaise
    • Insomnia
    • Nuetropenia (CBC)
    • Anemia (CBC)
    • Bone marrow suppression (CBC)
    • Granulocytopenia (CBC)
    • Hepatitis (Liver)
  3. Delavirdine
    Mechanism Side effects (3) DT (1) note (2)
    NNRTI

    • Nausea
    • Skin
    • Rash
    • Liver
    • function change (Liver)
    • Note:
    • Do NOT MIX TABLETS IN 3OZ+ WATER
  4. Indinavir
    Mechanism (1) Side effects (3) note (2)
    PI

    • Nausea
    • Diarrhea
    • Kidney stones
    • Note:
    • Hydrate (2-4 L/d)
    • DO NOT TAKE W/ GRAPEJUICE
  5. Didanosine
    Side effects (6) DT (4) Note (2)
    Mechanism
    • NRTI
    • GI intolerance
    • Bone marrow suppression (CBC)
    • Pancreatitis (serum amylase)
    • hepatitis (liver)
    • hyperuricemia (U/A)
    • painful peripheral neuropathy

    • Note:
    • used for pt's who cannot tolerate zidovudine.
    • MUST be chewed or dissolved to release buffer UNLESS Videx EC (time released)
  6. Efavirenz
    Side effects (6)
    Note (1)
    Mechanism
    • NNRTI
    • Rash
    • Dizziness
    • Trouble concentrating
    • Unusual dreams
    • Confusion
    • Encephalopathy (brain dysfunction)

    • Note:
    • take at bedtime to help w/ S.E
  7. Saquinavir
    S.E (3)
    Note (1)
    Mechanism
    • PI
    • nausea
    • headache
    • dirarrhea

    Note: Refrigerate capsules; ok at room temp for 90 DAYS
  8. Lamivudine
    S.E (2)
    Note (1)
    mechanism
    • NRTI
    • Nausea
    • Nasal Congestion

    • Note:
    • used to treat HIV and Hep B
  9. Combination Drugs
    mechanism
    • NRTI
    • Zidovudine and Lamivudine (Combivir)
    • Zidovudine Lamivudine Abacavir (Trizivir)
  10. Tenofovir
    S.E (2)
    mechanism
    • NRTI
    • nausea
    • vomitting
  11. Enfuvirtide
    S.E (4)
    Note (1)
    mechanism
    • FI/EI
    • nausea
    • skin irritation @ site
    • insomnia
    • peripheral nueropathy

    • Note:
    • INJECT SQ B.I.D ROTATE SITES
Author
jheneale
ID
15738
Card Set
HIV Drugs
Description
Antiretrovirals
Updated