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Acne Vulgaris
Most common form of acne
Blackhead
Open comedone
Comedone
Most characteristic sign of acne
Cysts
End product of pustules or nodules
Keratolysis
Softening and shredding of the horney outer layer of the skin
Keratolytic Agent
Skin peeling agent
Milia
Tiny little bumps of shed skin cells trapped in pockets on the skin.
Nodule
Ruptured pustules that form abscesses
Papule
Obstructed follicle that becomes inflamed
Pilosebaceous units (PSUs)
Consists of a sebaceous gland connected to a fine hair follicle
Pustule (pimples)
Larger lesions that are more inflamed than papules and can be superficial or deep
Whitehead
Closed comedone
Factors that Worsen Acne
1) changing hormone levels
2) oil from skin products
3) grease from work
4) pressure from sport equipment & backpacks
5) enviro irritants
6) squeezing or picking
7) aggressive scrubbing
8) stress
Drugs which Worsen Acne
1) anabolic steroids
2) bromides
3) corticosteroids
4) isoniazid
5) lithium
6) phenytoin
7) azathioprine
8) tetracycline
9) quinidine
10) B vitamins
Treatment of Mild Acne
Topical OTCs;
1) Keratolytics
2) Antibactetials
3) Benzoyl Perixide
Requires 4-8 weeks to see improvement
Comedolytics (keratolytics)
1) Salicylic Acid
2) Sulfer-Resorcinol Combo
Treats; black/white heads
Topical Antibacterials
1) Sulfer and sulfacetamide combo
Treats; acne, rosacea and seborrheic dermatitis
Benzoyl Peroxide
Most widely used OTC
Treats; noninflammatory acne
Treatment of Moderate Acne
1) physical exctraction
2) UV light therapy
3) oral antibiotics
4) vitamin A (retinoids)
5) Pr strength keratolytics
6) oral contraceptives
Oral Antibiotics for Acne
1) tetracycline
2) erythromycin
3) doxycycline
4) minocycline
Topical Antibiotics for Acne
1) clinamycin
2) erythromyin
3) metronidazole (cheapest)
4) sulfacetamide
Retinoids
1) adapalene - Differin
2) tretinoin - Retin-A
3) tazarotene
4) azelaic acid
Treatment of Severe Acne
1) surgical drainage
2) corticoid injections
3) isotretinoin
4) oral antibiotics
5) oral contraceptives
Isotretinoin
Accutane;
Treats in 15-20 weeks
AVOID PREGNANCY
Treatments for Hormonal Acne
1) oral contraceptives
2) corticosteroids
3) anti-androgens
Author
Cloe
ID
155593
Card Set
Unit 41.txt
Description
Chapter 41 of the Pharmacology for Pharmacy Technicians textbook by Moscou/Snipe
Updated
2012-05-24T06:19:36Z
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