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Antifungal
Drugs used to treat fungal infections
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Candida
- Type of fungus known as yeast
- Affects skin folds & mucous membranes
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Dermatophytes
Group of fungi responsible for most fungal skin, hair and nail infections
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Fungus
Primitive plant that reproduces by budding, releasing spores or fusing hyphae
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Mycoses
General term for fungal infections
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Onychomycoses
- Fungal infection of the nails.
- Aka tinea unguium
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Vulvovaginal Candidiasis
Vaginal Yeast Infection or Moniliasis
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Types of Fungi
Mold, Mildew, Yeast and Mushrooms
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tinea corporis
Ringworm of the body
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times capitis
Ringworm of the scalp
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tinea manus
Hand infection
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Preventing Athlete's Foot
- Keep clean and dry
- Wear open shoes to breathe
- Avoid bare feet in public area
- Wear cotton socks
- Change daily
- Use antifungal powders for prevetion
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Drugs causing Yeast Infection
- Antibiotics
- Corticosteroids
- The Pill
- Immunosuppressives
- Hormone Replacements
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How Anti-fungals Work
- 1) Destroy fungus cell membrane
- 2) Inhibit cell wall synthesis
- 3) interfer w/ nucleic acid synthesis
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Common Ending for Imidazoles and Triazoles
"-azoles"
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"-azoles" treat;
- Athlete's Foot
- Yeast Infections
- Jock Itch
- Ringworm
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"-azoles" work by;
Inhibit fungal cell wall synthesis
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"-azoles" Formulations
- Topicals; cream, gel, lotion, shampoo
- Oral;
- Suppositories;
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miconazole
Monistat 1, 3 & 7
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ketoconazole
Nizerol Shampoo
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Allyamine Antifungals
- terbinafine; Lamisil
- Prescription only
- Treats; nail infections
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Polyene Antifungal
- nystatin; Nystop
- Treats; candida infections
- Oral & Topical only
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Thiocarbamates
- tolnaftate; Tinactin, Dr Scholls
- Treats; Ringworm, Althlete's Foot & Jock Itch
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Echinocandin Antifungals
- "-fungin"
- Parental use only
- Treats Candida & Aspergillus
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ciclopirox
Treats Athlete's Foot, Ringworm & mild Onychomycosis
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grisefulvin
Oral tabs for Onychomycosis
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