Gram negative bacteria

type III secretion system (introduces exoenzymes S&T), endotoxin, Alginate capsule, pilli (adherence), Exotoxin A (disrupts protein synthesis), pyocyanin, LasA & LasB (degrade elastin), antibiotic resistance (beta lactamase),

slime layer, Pigments: pyocyanin (blue green- catalyzes production of superoxide and hydrogen peroxide & stimulates IL-8 release, leading to enhanced attraction of neutrophils) and fluorescein, transient in GI, corneal ulcers, hot tub folliculitis, pulmonary infections, UTIs,exotoxin A causes burn wound infections, Ecthyma gangrenosum

From Water, raw veggies, flowers and easily acquired in hospital setting

Rod pairs in shape, polar flagellum, aerobic, catalase +, oxidase +

Polysaccharide capsule, pili, cell wall (LPS), IgA proteases, facultative anaerobic

Cell wall componts impair ciliary fxn of resp tract, common cause of disease in unvaccinated children (meningitis, epiglottitis, cellulitis), grows in same media w/ Staph aureus

Facultative anaerobic, catalase +, oxidase +, non-motile, round rods

Facultative anaerobic, catalase +, oxidase +, non-motile, round rods bacteria. Where does it reside?

Tender, erythrematous papule on genital, chancroid (soft painful sore)

Polymyxin (antibiotic that binds LPS) resistance

Facultative anaerobic, catalase -, oxidase +, round rods. Where do they reside?

exotoxin (A&B subunits) inhibits negative regulator of adenylate cyclase --> ↑ cAMP, children younger than 1 at greater risk, whooping cough

Strictly aerobic, round rods, catalase +, oxidase +, non-motile, transmitted via respiratory droplets

Pertactin and filamentous hemagglutinin (binding), Adenylate cyclase/hemolysin (↑ cAMP, ↑ edema), tracheal cytotoxin, toxin that aids in attachmt & ↑ mucus secretion)

Diplococci that causes Urethral/vaginal discharge, dysuria, endocervicitis, pelvic inflam disease, ophthalmia in infants

Pilli, IgA protease, porin proteins, Opa proteins (outer membrane for binding/signaling), LOS (lipid A that lacks O antigen), beta-lactamase produces penicillin resistance diplococci

Non-motile aerobic diplococci present in human genital tract

Photophobia, petechial, purpuric, & rash, septicemia, thrombosis, Waterhouse-Friderichsen syndrome- over whelming disseminated intravascular coagulation, w/ bleeding into brain & adrenal gland

catalase +, oxidase + non-motile diplococci bacteria in human nasopharynx

Polysaccharide capsule, pilli, IgA protease, porin proteins, LOS (lipid A that lacks O antigen), transmitted via respiratory droplets and blood stream, diplococci

Zoonotic, Ulceroglandular tularemia; localized lymphadenopathy, Oculoglandular tularemia, Pneumonic tularemia

Polysaccharide capsule, Inhibits phagosome-lysosome fusion, beta lactamase, transmitted via tick bite, air, ingestion, and trauma

Spore forming,Q fever; small cell variants: extremely resistant to environmental stress and large cell variants: multiply in host monocytes or macrophages, Extremely stable in harsh environmental conditions, can survive in soil/milk for months- years, Vasculitis in skin, subcutane tissues, CNS, lungs, heart, kidneys, liver, spleen;

Transmitted via inhalation of aerosols of urine, feces, amniotic fluid, or placental tissue

Antigenic variation in expression of the cell wall LPS antigen, found in domestic livestock especially in pregnant animals

Strictly aerobic non-motile rod bacteria that you get from Cattle, goats, pigs (with bacteria from pigs getting most severe symptoms)

Inhibiting phagolysosome fusion, Suppressing production of TNF-α, Preventing release of toxic enzymes from intracellular granules, induce granuloma formation. Transmitted via Contact w/ animals, unpasturized dairy

Zoonotic, non-encapsulated, nonfermenter, splenomegaly, intensity of fever and symptoms recur and recede at about 10 day intervals (aerobic rod bacteria)

Extremely sensitive to O2, endarteritis lesions, Nontender chancre, mucocutaneous rash; condylomata lata (Raised lesions, wartlike, highly infectious), Granulomatous lesions, congenital form in infants (deafness, teeth/bone malformation)

Thin helical bacteria, sexually transmitted, Resist phagocytosis, adhere to host fibronectin, hyaluronidase facilitates perivascular infiltration

Anaerobic, non-polar flagella, thin helical bacteria in human genital tract

No cell wall, urease +, opportunistic, Nongonococcl urethritis

#1 tick borne disease in US, erythema migrans (bulls-eye lesions), facial nerve palsy, zoonotic, linked to non-Hodgkin lymphomas

Present in White-footed mice, white-tailed deer

Virulence factors mainly unknown but bacteria is Motility,and can survive in absence of iron

Microaerobic, non-polar flagella, helical bacteria

Slime layer, Rocky mountain spotted fever (rash, myalgia, fever, vomit, confusion), typhus, GI, periorbital swelling, stiff neck

Giemsa stain, Specific fluorescein-labeled Abs, PCR, non-motile small bacillus aerobic bacteria

Transmitted via hard shelled ticks, aerobic bacteria, only found in cytoplasm of eukaryotic cells of small wild animals

P1 adhesin (adheres & inhibits ciliary action), superantigen (elicits production of TNF-α, IL1, IL6), very small bacteria shape unknown

PCR, Mulberry-shaped colonies on media containing sterols, ELISA & Immunofluorescence assays. Present in human respiratory tract

PCR, Mulberry-shaped colonies on media containing sterols, ELISA & Immunofluorescence assays. Present in human respiratory tract. What's the O2 requirement?

No cell wall, urease +, opportunistic, Nongonococcl urethritis, Adherence proteins, inhibits host catalase, activate macrophages and cytokine production. What's the O2 requirement?

swineherd’s disease; swamp or mud fever), headache, myalgia, chills, ab pain, & conjunctivitis, Severe disease can progress to vascular collapse,
thrombocytopenia, hemorrhage, & hepatic/renal dysfunction

what's the O2 requirement for Leptospira interrogans

Thin helical bacteria w/ hooks, found in rodents and other small animals