Vasopressin

• Hormone
• Vasopressor

Polypeptide hormone extracted from the posterior pituitaries of animals. It possesses pressor and antidiuretic hormone properties. Conclusive evidence supporting the use of vasopressin in cardiac arrest is lacking

Vasopressin, in higher doses, acts as a non-alpha-adrenergic vasoconstrictor through direct stimulation of smooth muscle receptors. It can be used as an alternative to epi during cardiac arrest

• Onset: Varies
• Peak: Varies
• Duration: 30-60 min
• Half-life: 10-20 min

• Used to increase peripheral vascular resistance during CPR as an alternative to or after epi has been used.
• 1 Dose may replace the first or second dose of epi in cardiac arrest

None for Cardiac arrest

• Epilepsy
• Migraine
• Asthma
• Heart failure
• Angina

• Skin blanching
• Abdominal cramps
• Nausea
• Hypertension
• Bradycardia
• Minor arrythmias

40 units

Not indicated

1 dose

IV/IO

Vials