NUR 119 Ch 1 Points

  1. Do IV routed drugs have a pharmaceutic phase - Yes or No - and why or why not?
    No - the pharmaceutic phase is the drug "becoming a solution" so that it may cross the biologic membrane. IV, IM and subq routed drugs are already in solution, hense no pharmaceutic phase.
  2. Decreased AAAA will alter drug elimination.
    kidney function
  3. Drug elimination is most often via the AAAA, although elimination may also take place via the [7 factors?].
    • a. kidney
    • liver
    • bile
    • feces
    • lungs
    • saliva
    • sweat
    • breast milk
  4. Metabolism or biotransformation may occur in either the AAAA or the BBBB. Most often it takes place in the BBBB.
    • a. GI tract
    • b. liver
  5. The term distribution refers to the drug becoming available to body fluids and body tissues. Distribution is influenced by [4 factors?].
    • blood flow
    • affinity to the tissue
    • drug dosage
    • drug concentration in the body
  6. Drug absorption can be altered by [8 factors?].
    • blood flow
    • pain
    • stress
    • hunger
    • fasting
    • food
    • pH
    • method of administration
  7. AAAA is accomplished by cells BBBB a drug particle to carry the drug across the membrane.
    • a. Pinocytosis
    • b. engulfing
  8. Active absorption requires energy to move a drug AAAA.
    against a concentration gradient
  9. Passive absorption takes place without energy, by AAAA.
  10. AAAA is the movement of the drug to the body fluids. It takes place by BBBB absorption, active absorption, and DDDD.
    • a. Absorption
    • b. passive
    • c. passive
    • d. pinocytosis
  11. The four parts of the AAAA phase achieve drug action. These phases are BBBB, CCCC, metabolism or DDDD, and excretion or EEEE.
    • a. pharmacokinetics
    • b. absorption
    • c. distribution
    • d. biotransformation
    • e. elimination
  12. In the AAAA phase, drugs become a solution. This phase takes place in the gastrointestinal, or GI, tract; thus it is absent with BBBB administration.
    • a. Pharmaceutic
    • b. parenteral
  13. The term AAAA refers to the effects of drug concentration on the body systems.
  14. To understand the AAAA of a drug, the nurse must understand the BBBB
    • a. pharmacodynamics
    • b. different aspects of drug action.
  15. One important aspect is the AAAA, BBBB, and duration of action of a drug.
    • a. onset
    • b. peak
  16. The onset of action is the time necessary for the drug to reach AAAA effectiveness.
  17. The peak action occurs when the drug reaches the AAAA.
    highest blood concentration
  18. The AAAA is the length of time the drug has BBBB
    • a. duration of action
    • b. pharmacologic effects
  19. Drugs that produce a response are called AAAA. Drugs that block responses are called BBBB.
    • a. agonists
    • b. antagonists
  20. The term AAAA refers to the lack of specific or selective effects of many drugs. While these drugs work on BBBB, they may affect these receptors in all locations in which the receptor is found. This causes the drug to alter function dependent on where the receptor is located.
    • a. nonspecific drug effects
    • b. only one type of receptor
  21. AAAA drugs are drugs that activate many different types of receptors, again causing a BBBB from the different receptor sites.
    • a. Nonselective
    • b. variety of responses
  22. There are AAAA categories of drug action.
  23. Drugs that are AAAA increase the rate of cell activity or gland secretion.
  24. Drugs that are AAAA decrease the rate of cell or gland activity.
  25. Replacement drugs replace essential AAAA no longer existing in the body.
    body compounds
  26. Drugs that inhibit or kill organisms AAAA with cell growth.
  27. Drugs that are considered irritants cause irritation, which affects the AAAA.
    desired action
  28. The half-life of a drug, or the time it takes for one half of the drug concentration to be eliminated, can be used to AAAA.
    guide drug dosage intervals
  29. The safety of drug administration is maintained by using the AAAA and BBBB of drugs.
    • a. therapeutic index
    • b. therapeutic range
  30. A AAAA therapeutic index refers to a drug with a BBBB safe level. Patients taking these drugs need to have their serum drug levels monitored closely.
    • a. low
    • b. narrow
  31. Drugs with a AAAA therapeutic index are considered to have a BBBB safe level and do not require routine serum drug level monitoring.
    • a. high
    • b. wide
  32. The AAAA range refers to the range of serum drug level that allows the drug to be effective but remain below the level that would cause BBBB.
    • a. therapeutic
    • b. toxic effect
  33. Monitoring AAAA drug levels is the method used to measure serum drug levels for those drugs with BBBB therapeutic indexes. The peak level is the highest serum concentration, and it measures the CCCC. The trough is the lowest serum concentration, and it measures the DDDD.
    • a. peak and trough
    • b. narrow
    • c. rate of absorption of the drug
    • d. rate of drug elimination
  34. Loading doses are used to achieve AAAA drug concentrations.
    rapid minimum serum
  35. Drug side effects are effects that are other than the effects intended. AAAA drugs have side effects, some of which are BBBB.
    • a. All
    • b. undesirable
  36. AAAA are more severe than side effects and are always BBBB. They may be mild or severe.
    • a. Adverse reactions
    • b. undesirable.
  37. Toxicity or toxic effects are identified by monitoring the AAAA of drugs. When a drug exceeds the therapeutic range, BBBB occur.
    • a. serum therapeutic ranges
    • b. toxic effects of the drug
  38. Drug AAAA refers to decreased effectiveness of a drug over BBBB.
    • a. tolerance
    • b. the course of therapy
Card Set
NUR 119 Ch 1 Points
Drug Action: Pharmaceutic, Pharmacokinetic, and Pharmacodynamic Phases Points