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Interaction/Reaction: Induction of P-450 enzymes
Barbiturates, phenytoin, carbamazepine, rifampin, quinidine, giseofulvin
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Interaction/Reaction: Inhibition of P-450 enzymes
Cimetidine, ketoconazole, INH, grapefruit, erythromycin, sulfonamides
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Interaction/Reaction: Metabolism by P-450 enzymes
Benzos, amide anesthetics, metoprolol, propranolol, nifedipine, phenytoin, quinidine, theophylline, warfarin, barbiturates
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Interaction/Reaction: Increased risk of digoxin toxicity
Quinidine, cimetidine, amiodarone, CCBs
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Interaction/Reaction: Competition for albumin-binding sites
Warfarin, ASA, phenytoin
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Interaction/Reaction: Blood dyscrasias
Ibuprofen, quinidine, methyldopa, chemotherapeutic agents
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Interaction/Reaction: Hemolysis in G6PD-deficient patients
Sulfonamides, INH, ASA, ibuprofen, nitrofurantoin, primaquine, pyrimethamine, chloramphenicol
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Interaction/Reaction: Gynecomastia
Spironolactone, Estrogens, Digitalis, Cimetidine, chronic Alcohol use, Ketoconazole
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Interaction/Reaction: SJS
Ethosuximide, sulfonamides
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Interaction/Reaction: Photosensitivity
Tetracycline, amiodarone, sulfonamides
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Interaction/Reaction: Drug-induced SLE
Procainamide, hydralazine, INH, penicillamine, chlorpromazine, methyldopa, quinidine
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