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Why do we use PA drugs?
- Sedate and calm the pt
- Pre-emptive analgesia
- Prevent movement
- Balanced Anesthesia
- Smooth recovery
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PA Drugs given
IM / SQ 30mins prior
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Anticholinergics
- Atropine Sulfate (Atropine)
- Glycopyrrolate (Robinul-V)
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Anticholinergics Main effects
- Dry secretions
- Prevent Bradycardia
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Anticholinergics reactions
- May cause intial bradycardia after IV admin
- Arrythmias after IV admin
- Colic in horses
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Anticholinergics when to use
- Small animal : with bradycardic animals
- Larger : Don't
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Atropine Specifics (Brand, Prevents/Reduce, Treats, Antidote, Contra)
- Brand name: Atropine
- Prevents/Reduces : Secretions
- Treats: Bradycardia & AV blocks
- Contraindications: Don't use in tachycardic pt / Dont use in animals with constipation
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Glycopyrrolate Specifics (Brand, Advantages)
- Brand Name: Robinul-V
- Advantages: 1. Can use for tachycardic pts
- 2. Use for longer procedures
- 3. Opthalmic surgery
- 4. Neurosurgery
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Tranqs 3 Groups
- Phenothiazines
- Benzodiazepines
- Butyrophenones
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Properties of Tranqs as PA drugs
- 1. Relaxation and Calmness
- 2. No analgesia
- 3. Manages pts fear, anxiety
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Phenothiazines Drugs
Acepromazine (Promace)
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Benzodiazepines Drugs
- Diazepam (Valium)
- Midazolam (Versed)
- Zolezepam (in Telazol)
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Butyrophenones Drugs
Droperidol (in Innovar-Vet)
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Acepromazine Effects / Side effects
- Effects: 1. Water Soluble
- 2. Mental calming, decreased moter activity
- 3. Improves anagesic effects of other anagesic drugs activity
- Side: 1. Hypotension
- 2. Hypothermia
- 3. Lowers the seizure threshold
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Diazepam / Midazolam / Zolazepam (Effects, Side Effects, Indications)
- Effects: 1. Skeletal muscle relaxtion
- 2. Anticonvulsant
- Side: 1. aggro in cats
- 2. Ataxia
Indication: Seizures , High margin of safety, calming affects in aminals
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Droperidol Specifics
- Dec CO
- combined with fentanyl
- Neuroleptanalgesia
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Sedatives / Alpha-2-Agonists (Drugs/Effects/Side)
- Xylazine (Rompun, Anased)
- Medetomidine (Domitor)
- Detomidine (Demosedan)
- Dexmedetomidine (Dex Domitor)
1.Produces calming, sedation, muscle relaxation
1.Bradycardia
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Xylazine Effects / Side
1. Good muscle relaxation
1. vomiting in dogs and cats
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Medetomidine Effects / Side
1. Powerful Analgesic
1.Causes profound bradycardia
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Opioids (sites/classes)
- 1. Mu - sever pain
- 2. Kappa - Moderate pain
- 3. Sigma - Chronic pain
- 1.Pure Agonist - Stimulate all
- 2.Mixed - Stimulate and block some
- 3.Pure Atagonist - Block all
- 4.Partial Agonist - Stimulate certain ones
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Morphine (Advan/Disadvan/class)
- 1.inexpensive
- 2.good sedation
- 3.good analgesia
- 1.may cause bradycardia and resp. depression
- 2.see mania in cats
Pure Agonist
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Oxymorphone (Brand/Potency/Adv/Dis/Class)
- Brand: Numophan
- 5-10x
- 1.Great sedation
- 2. good analgesia
Pure Agonist
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Fentanyl (Brand/Poten/Advan/Disadvan/Class)
1.Mild sedation/good analgesia
1.Decrease in tidal volume
Pure Agonist
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Butorphanol (Brand/Class/Poten/Advan/Dis)
- Torbugesic
- Mixed opioid
- 2-5x
- 1.Has ceiling effect
- 2.Visceral analgesia
- 1.Not reliable sedation alone
- 2.Controlled substance
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Buprenorphine (Brand/class/ADvan/Disadvan)
- Buprenex
- Partial Agonist
- 1.Schedule 3
- 2.long term analgesia
- 1.Has strong affinity for its receptors
- 2.Not reliable sedation when alone
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M-99 (Brand/Class/Poten)
- Etorphine
- 1000x
- must have Naloxone rdy
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Hydromorphone (Brand/Class/stuff)
- Dilaudid
- Pure agonist
- 3x
- in cats
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Reversal Agents
- Naloxone (Narcan)
- Nalbuphine (Nubaine)
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NSAID's 3 effects (Stands for) Drugs
- Non Steriodal antinflammatory drugs
- 1.Anti-inflam
- 2.Analgesics
- 3.Anti-pyretic
- Phenylbutazone
- Carprofen
- Deracoxib
- Tepoxalin
- Acetominopehn
- Meloxicam
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Phenylbutazone
- Butazolidin
- Horses
- Toxic dogs cats
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Carprofen
- Rimadyl
- Used in dogs
- no cats
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PA Deff
period of time that immediately precedes the induction period in which you prepare yourself and pt for anesthetic protocol
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PA procedures
- Assess pt
- collect data
- fast
- give PA drugs
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Reasons for placing IV cath
- Allow fo admin of surgical fluids
- -prevent hypotension
- Allow for rapid easy admin of Emergency drugs
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IV cath risks
- Introduction to air
- broken cath tip
- accidental overhydration
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ET Tubes
- Murphy - eye
- Cole - no cuff
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Norms (Temp/HR/RR)
- Cats - 101.5 +/- 1F , 140-240bpm, 20-30rpm
- Dogs , 60-160bpm, 15-30rpm
- Equines 100 +/- 1F , 30-40bpm, 10-20rpm
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