-
maintains the electrolyte, acid-base & fluid balance of the blood & is the major homestatic organ of the body:
kidneys
-
drains urine from kidneys & conducts it by peristalis to bladder:
ureters
-
temporary storage area for urine:
urinary bladder
-
drains the bladder:
urethra
-
normal characteristics of urine:
- clear & pale to deep yellow
- slightly aromatic
- pH ranges from 4.5 - 8.0, but average is 6.0 & slightly acidic
- specific gravity ranges from 1.001-1.030
-
abnormal urinary constituents & conditions:
- glucose - glycosuria
- ketone bodies - ketonuria
- proteins - proteinuria (albuminuria)
- pus (WBCs & bacteria) - pyuria
- RBCs - hematuria
- hemoglobin - hemoglobinuria
- bile pigments - bilirubinuria
-
excessive intake of sugary foods/diabetes mellitus:
glycosuria
-
starvation; diabetes mellitus when coupled
ketonuria
-
physical exertion, pregnancy/glomerulonephritis (inflammation of the kidneys), hypertension:
proteinuria(albuminuria)
-
urinary tract infection:
- pyuria
- bleeding in the urinary tract (due to trauma, kidney stones, infection):
- hematuria
-
transfusion reaction, hemolytic anemia (RBCs are rupturing):
hemoglobinuria
-
liver disease (hepatitis):
bilirubinuria
-
a microscopic tubule consisting of two major parts=glomerulus & renal tubule:
nephron
-
tangled capillary knot that filters fluid from the blood into the lumen of the renal tubule:
glomerulus
-
function is to process fluid filtered from the blood:
renal tubule
-
the beginning of the renal tubule is an enlarged end called:
glomerular capsule
-
the glomerulus & the glomerular capsule together are called:
renal corpuscle
-
the anatomical parts of the renal tubule are:
- proximal convoluted tubule
- loop of Henle
- distal convoluted tubule
-
is a passive process in which fluid passes from the lumen of the glomerular capillary into the glomerular capsule of the renal tubule:
glomerular filtration
-
moves most of the filtrate back into the blood, leaving principally salt water plus wastes in the lumen of the tubule:
tubular reabsorption
-
is essentially the reverse of tubular reabsorption & is a process by which the kidneys can rid the blood of additional unwanted substances such as creatinine & ammonia:
tubular secretion
-
is used to denote the hydrogen ion concentration [H+] in body fluids:
pH
-
the pH of a body's fluids is also referred to as its:
acid-base balance
-
a substance that releases H+ in solution(such as body fluids):
acid
-
a substance, often a hydroxyl ion (OH-) or bicarbonate ion (HCO3-), that binds to H+:
base
-
when pH levels fall below 7.35, the body is said to be in a state of:
acidosis
-
when pH levels rise above 7.45, the body is said to be in a state of:
alkalosis
-
a condition of too little carbon dioxide in the blood:
respiratory alkalosis
-
is the result of impaired respiration or hypoventilation which leads to the accumulation of too much carbon dioxide in the blood:
-
is characterized by low plasma HCO3- and pH:
metabolic acidosis
-
is characterized by elevated plasma HCO3- and pH:
metabolic alkalosis
-
the effect of increasing the afferent radius on glomerular filtration rate & glomerular pressure:
both rate & pressure increased
-
the effect of decreasing the efferent radius on glomerular filtration rate & glomerular pressure:
both rate & pressure increased
-
the effect of increasing the beaker pressure on glomerular filtration rate:
rate increased
-
the effect of increasing the beaker pressure on glomerular pressure:
pressure increased
-
what was the glomerular filtration rate at 80mm Hg beaker pressure, 0.55 mm afferent radius, and 0.45 efferent radius:
129.61
-
with the beaker pressure increased to 85 mm Hg, at what afferent radius was the glomerular filtration rate in question 7 restored:
0.52 mm
-
with the beaker pressure increased to 85 mm Hg, at what efferent radius was the glomerular filtration rate in question 7 restored:
0.52mm
-
3 steps of urine formation:
- glomerular filtration
- tubular reabsorption
- tubular secretion
-
works to reaborb sodium ions (and thereby water) at the expense of losing potassium ions; its site of action is the distal convoluted tubule; produced by the adrenal gland:
aldosterone
-
makes the distal tubule and collecting duct more permeable to water, thereby allowing the body to reabsorb water from the filtrate when its present; manufactured by the hypothalamus:
ADH
-
facilitate the transport of glucose over a plasma membrane
glucose carriers
-
Used to denote the hydrogen ion concentration in body fluids
pH
-
Normal pH values
7.35-7.45
-
Composed of a mixture of weak acids and weak bases. Regulate pH levels by binding H+ and removing it from solution as its concentration begins to rise or fall.
Chemical buffer
-
Has 2 major buffers (renal and respiratory). Help regulate body pH by controlling the output of acids, bases, or carbon dioxide from the body.
Physiological buffer
-
Relationship between CO2 and pH
If more CO2 accumulates in body, it lowers the pH
-
How does the physiological buffer respond to different CO2 & pH levels
- Too much acid...execretes more H+in urine.
- Too much CO2... generates more H+ in body
-
How metabolic rate affects pH and CO2 rates
- Increase in metabolism...lowers pH causing acidosis
- Decrease in metabolism...less CO2, raises pH, causing alkalosis
-
Cells that contain a nucleus
eukaryotes
-
During cell reproduction the DNA coils and forms
chromosomes
-
Specialized sex cells are called
gametes (sperm, egg)
-
Sex cells combine and form the first cell of a new individual through a process called
fertilization
-
-
In plants, a male gamete is called
- sperm
- A female is called
- ova
-
In animals, a male gamete is called
- sperm
- A female is called
- egg
-
Meiosis is also known as
reduction division
-
What does meiosis do
Reduces the number of chromosomes in gametes to 1/2 the number contained in a parent cell
-
2 copies of each chromosome is known as
diploid (2n)
-
1 copy of each chromosome is known as
haploid (n)
-
Plants undergo ________ __ _________ in its life cycle
alternation of generation
-
Name the 2 divisions of meiosis
I and II
-
Name the order of stages in Stage I of meiosis
Prophase I, Metaphase I, Anaphase I, Telephase I, Cytokinesis I
-
Name the order of stages in Stage II of meiosis
Prophase II, Metaphase II, Anaphase II, Telephase II, Cytokinesis II
-
During this phase the diploid has already doubled its DNA to become tetraploid
Prophase I
-
Matched pairs
homologous chromosomes
-
Crossing over
Mixing of genetics
-
Phase that shows the formation of the spindle;tetrads align at equator of the cell
Metaphase I
-
Phase where homologous chromosomes seperate, but sister chromatids stay together and move to opposite ends of the cell
Anaphase I
-
Phase where the chromosomes gather at the poles and uncoil to thin, threadlike form
Telephase; Cytokinesis I
-
Thin, threadlike forms are
Chromatin
-
Phase where chromosomes coil and nuclear membrane disappears
Prophase II
-
Phase where spindle formsand sister pairs align at the equator of cell
Metaphase II
-
Sister chromatids seperate
Anaphase II
-
Phase where chromatids reach the poles and uncoil into thin, threadlike chromatin
Telephase II
-
Phase where two diploid daughter cells formed in the first division are physically divided into tow haploid daughter cells
Cytokinesis II
-
A male produces ____ haploid sperm
4
-
This enables the male to produce sperm
primary sperm atocyte
-
A female produce ____egg and _____ smaller remnants
1 & 3
-
The smaller remnants that female produce are called
polar bodies
-
Passing of traits or characterisitics from one generation to the next
Heredity
-
Humans have a total of ______ chromosomes, _______from male and _______female
46, 23, 23
-
These express themselves even when just one copy is present
dominant genes
-
These express themselves only when 2 copies are present
recessive genes
-
These are used to designate dominant genes
Capital letters
-
These represent recessive genes
lowercase letters
-
An individual with 2 dominant and 2 recessive genes is called
homozygous
-
An individual with 1 dominant and 1 recessive gene is called
heterzygous
-
The genetic makeup of an individual is called
genotype
-
Shows the transmission of a genetic trait through generations of family
pedigree
-
Useful for detemining the genotype of a person as well as predicting genotypes of future generations
pedigree
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